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Phytochemical investigation and assessment of the anti-inflammatory activity of four taxa growing in Turkey.
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Centro de Investigación en Ingeniería de Materiales, Facultad de Medicina y Ciencias de la Salud, Universidad Central de Chile, Santiago, Chile.
Introduction: L. has been known as "hogweed" and used for inflammatory diseases, including fever, enteritis, and bronchitis, for many years worldwide. The genus is also prominently recognized for its high content of coumarins, which are considered a significant group of natural compounds known for their noteworthy anti-inflammatory properties.
View Article and Find Full Text PDFBergenin, a bioactive flavonoid: advancements in the prospects of anticancer mechanism, pharmacokinetics and nanoformulations.
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Department of Pathology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
The natural world is a vast reservoir of exceptionally varied and inventive chemical compositions. Natural products are used as initial compounds to create combinatorial libraries by targeted modifications and then by analyzing their structure-activity connections. This stage is regarded as a crucial milestone in drug discovery and development.
View Article and Find Full Text PDFEditorial: Women in ethnopharmacology: 2023.
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Department of Functional Sciences I/Biochemistry, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
An updated review summarizing the anticancer potential of flavonoids via targeting NF-kB pathway.
Front Pharmacol
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KM Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.
Nuclear factor-κB (NF-κB) cell signaling pathway is essential for the progression and development of numerous human disorders, including cancer. NF-κB signaling pathway regulates a wide range of physiological processes, such as cell survival, growth, and migration. Deregulated NF-kB signaling resulted in unregulated cell proliferation, viability, movement, and invasion, thus promoting tumor development.
View Article and Find Full Text PDFWhole-genome sequencing and secondary metabolite exploration of the novel BN with broad-spectrum antagonistic activity against fungal plant pathogens.
Front Microbiol
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School of Biological and Pharmaceutical Engineering, Lanzhou Jiaotong University, Lanzhou, Gansu, China.
The utilization of chemical pesticides recovers 30%-40% of food losses. However, their application has also triggered a series of problems, including food safety, environmental pollution, pesticide resistance, and incidents of poisoning. Consequently, green pesticides are increasingly seen as viable alternatives to their chemical counterparts.
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