Bioactive constituents and action mechanism of Xiaoyao San for treatment of non-alcoholic fatty liver disease.

World J Hepatol

Jiangsu Engineering Research Center of Cardiovascular Drugs Targeting Endothelial Cells, College of Health Sciences, School of Life Sciences, Jiangsu Normal University, Xuzhou 221000, Jiangsu Province, China.

Published: October 2024

AI Article Synopsis

  • Xiaoyao San (XYS) is a traditional Chinese medicine used to alleviate "liver stagnation and spleen deficiency" symptoms by soothing the liver, tonifying the spleen, and nourishing the blood.
  • XYS has been historically applied in treating conditions like depression, indigestion, and liver diseases.
  • Recent research highlights the importance of identifying the bioactive components and mechanisms of XYS, particularly for its potential use in treating non-alcoholic fatty liver disease.

Article Abstract

Xiaoyao San (XYS) is a classic Chinese medicine prescription. It is traditionally used to relieve syndrome of "liver stagnation and spleen deficiency", a common syndrome type in traditional Chinese medicine, through soothing liver, tonifying spleen, and nourishing blood. Correspondingly, XYS has long application in the treatment of depression, dyspepsia and liver diseases. Given the rising of cutting-edge researches on XYS, there's a significant need to diligently uncover the bioactive constituents and action mechanisms of XYS for treating non-alcoholic fatty liver disease accordingly.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514614PMC
http://dx.doi.org/10.4254/wjh.v16.i10.1213DOI Listing

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