AI Article Synopsis
- Diagnostic algorithms for syphilis primarily rely on serology testing, which can sometimes be ineffective due to immunosuppressive therapies.
- A case is presented involving a patient with multiple sclerosis receiving ofatumumab who developed secondary syphilis.
- Despite the diagnosis, this individual showed persistent negative results for both treponemal and nontreponemal tests, complicating the diagnosis.
Article Abstract
Diagnostic algorithms for syphilis are based on serology. However, with the advent of immunosuppressive therapies, these algorithms may fail. We report a case of an individual with multiple sclerosis on treatment with ofatumumab and secondary syphilis with visual and auditory systems involvement and persistent negative treponemal and nontreponemal tests.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521249 | PMC |
| http://dx.doi.org/10.1093/ofid/ofae563 | DOI Listing |
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