Some children socially transition genders by changing their pronouns (and often names, hairstyles, clothing) from those associated with their assigned sex at birth to those associated with their gender identity. We refer to children who have socially transitioned as transgender children. In a prospective sample of children who socially transitioned during childhood (at or before the age of 12; = 6.82), we tested whether the parent-reported internalizing symptoms of transgender children were different before vs. after they socially transitioned. The children were predominantly white (70.6% white) and girls (76.5% transgender girls, 23.5% transgender boys). Their parents tended to have high levels of education (74.5% Bachelor's degree or above) and lived in families with high household incomes (62.7% with household incomes of $75,000 or above). On average, youth showed lower levels of internalizing symptoms after socially transitioning vs. before, suggesting a possible mental health benefit of these transitions.
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http://dx.doi.org/10.1177/21677026231208086 | DOI Listing |
Genet Med
January 2025
Genomics Ethics, and Translational Research Program, RTI International, Research Triangle Park, NC; Department of Translational and Applied Genomics, Kaiser Permanente Center for Health Research, Portland, OR. Electronic address:
Purpose: Limited evidence evaluates parents' perceptions of their child's clinical genomic sequencing (GS) results, particularly among individuals from medically underserved groups. Five Clinical Sequencing Evidence-Generating Research (CSER) consortium studies performed GS in children with suspected genetic conditions with high proportions of individuals from underserved groups to address this evidence gap.
Methods: Parents completed surveys of perceived understanding, personal utility, and test-related distress after GS result disclosure.
Genet Med
January 2025
Newborn Screening Ontario, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada; Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa. Electronic address:
Purpose: Universal newborn hearing screening (UNHS) programs using audiometric techniques alone are limited in ability to detect non-congenital childhood permanent hearing loss (PHL). In 2019, Ontario launched universal newborn screening (NBS) for PHL risk factors: congenital cytomegalovirus (cCMV) and 22 common variants in GJB2 and SLC26A4. Here we describe our experience with genetic risk factor screening.
View Article and Find Full Text PDFDev Med Child Neurol
January 2025
Speech and Language, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Aim: To examine the adaptive behaviour profiles of children with monogenic neurodevelopmental disorders (NDDs) to determine whether syndrome-specific or transdiagnostic approaches provide a better understanding of the adaptive behavioural phenotypes of these NDDs.
Method: This cross-sectional study included parents and caregivers of 243 (48% female) individuals (age range = 1-25 years; mean = 8 years 10 months, SD = 5 years 8 months) with genetically confirmed monogenic NDDs (CDK13, DYRK1A, FOXP2, KAT6A, KANSL1, SETBP1, BRPF1, and DDX3X). Parents and caregivers completed the Vineland Adaptive Behavior Scales, Third Edition to assess communication, daily living, socialization, and motor skills.
Appl Econ Lett
September 2023
Vienna Institute for International Economic Studies (Wiiw), Vienna, Austria.
This paper analyses whether government spending for social protection contributed more to counteracting the COVID-19 crisis than in previous episodes. Based on data for 27 EU countries over 1995-2021, we find that social spending is countercyclical and contributed to stabilization during the pandemic. However, we do not find evidence that overall social spending during 2020-2021 was more countercyclical then before.
View Article and Find Full Text PDFFront Med (Lausanne)
January 2025
Ethiopian Statistical Services, Bahirdar, Ethiopia.
Background: Irrational use of medicines is a problem globally that soon needs to be addressed. According to estimates from the World Health Organization, almost half of all medications were improperly prescribed. This study aimed to assess the drug prescribing patterns based on World Health Organization drug use indicators in the dermatology outpatient department of Injibara General Hospital.
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