AI Article Synopsis

  • Acute upper gastrointestinal bleeding (UGIB) often results from peptic ulcer disease or variceal bleeding, but rare causes like renal cell carcinoma (RCC) can also be involved.
  • A 55-year-old male experienced melena and right flank pain, leading to the discovery of active bleeding in the duodenum via esophagogastroduodenoscopy (EGD).
  • Imaging revealed a duodenorenal fistula caused by RCC, highlighting the need for thorough evaluations to uncover uncommon causes of UGIB.

Article Abstract

Acute upper gastrointestinal bleeding (UGIB) is a medical emergency with most common cause being peptic ulcer disease (PUD) or variceal bleeding. However, cancers that cause UGIB by invading the small intestine are uncommon, and the invasion of renal cell carcinoma (RCC) into the duodenum is an even rarer occurrence. A 55-year-old male presented with melena and right flank pain. Esophagogastroduodenoscopy (EGD) revealed an active bleeding source in the duodenum, later identified on contrast-enhanced computed tomography (CECT) as a duodenorenal fistula (DRF) caused by direct extension of the RCC. The imaging confirmed the presence of a malignant renal mass infiltrating adjacent organs. This atypical presentation of RCC with DRF manifesting as UGIB underscores the importance of comprehensive evaluations in cases of gastrointestinal bleeding to identify rare underlying causes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11519071PMC
http://dx.doi.org/10.1155/2024/7122744DOI Listing

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