Dysbiosis and colonic adenoma: The lethal link?

World J Clin Oncol

Department of Pediatric Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry 605006, India.

Published: October 2024

AI Article Synopsis

  • - Gut dysbiosis occurs when the normal gut microbiome is disrupted, creating a harmful environment in the colon.
  • - This disruption can lead to changes in cellular signals that may contribute to the development of mucosal outgrowths like polyps.
  • - Understanding the mechanisms connecting gut dysbiosis to colonic polyps could shed light on important health implications.

Article Abstract

Gut dysbiosis, a phenomenon in which the existing commensal microbiome changes to an adverse microenvironment in the colon, is thought to lead to altered cellular signals. How this is involved in producing mucosal outgrowths such as polyps in the colon is intriguing. Deciphering the various mechanisms involved provides an in-depth understanding of the link between gut dysbiosis and colonic polyps.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514503PMC
http://dx.doi.org/10.5306/wjco.v15.i10.1376DOI Listing

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