Introduction: The identification of geriatric syndromes in people with dementia is important. The aim of the study was to assess the prevalence of geriatric syndromes among dementia outpatients.
Methods: A cross-sectional study was conducted enrolling outpatients with dementia aged ≥60 years old. Dementia was diagnosed by neuropsychiatrists following DSM-5 criteria. The geriatric syndromes assessed included nutritional status (Mini Nutritional Assessment Scale-Short Form), polypharmacy, comorbidities, alcohol use, depression (quality of life in Alzheimer disease), functional status (Barthel Index, Instrumental Activities of Daily Living); lower body strength (30 s stand chair test), and frailty (Timed Up and Go test ≥14 s).
Results: A total of 87 participants was recruited in the study (mean age: 76.8 ± 1.2 years; female: 65.5%). The median number of geriatric syndromes per participant was 5 (IQR = 2); all participants had two or more geriatric syndromes. The most common geriatric syndromes were loss of independence (96.6% impairment in >1 IADL task score and 74.7% dependency in physical function at based on Barthel Index), reduced lower body strength (86.2%), malnutrition and risk of malnutrition (78.2%), and frailty (67.8%). Current and history of smoking, drinking alcohol, using memantine therapy, malnourishment and risk of malnourishment were significantly associated with increasing severity of dementia.
Conclusion: The presence and coincidence of geriatric syndromes is common among outpatients with dementia. These findings have important clinical implications in terms of the assessment and service delivery for older adults in Vietnam. We are exploring ways to enhance our services to provide comprehensive, multidisciplinary approaches to screening, recognition, and treatment of geriatric syndromes in older adults with dementia.
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http://dx.doi.org/10.1159/000541237 | DOI Listing |
Maturitas
December 2024
Department of Translational and Precision Medicine, Sapienza-University of Rome, Viale del Policlinico 155, Rome 00161, Italy. Electronic address:
Sleep-disordered breathing is a highly prevalent disorder with negative impact on healthcare systems worldwide. This condition has detrimental effects on cardiovascular health and quality of life, and is frequently associated with a variety of comorbidities, including cardiovascular disease, heart failure, diabetes and atrial fibrillation. Nevertheless, it remains frequently undiagnosed and undertreated, especially in specific populations.
View Article and Find Full Text PDFAging Clin Exp Res
December 2024
Endocrinology & Metabolism Research Institute, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Background: Depression is one of the most debilitating mental disorders and a risk factor for many other chronic diseases that are commonly seen in the geriatric population. It has been claimed in previous studies that depression can be associated with obesity in this age group, but there is no common consensus between their results.
Aim: This study aims to evaluate the association between depression metabolic syndrome and obesity phenotypes in community-dwelling older adults living in the East of Iran.
Cell Metab
December 2024
State Key Laboratory of Membrane Biology, MOE Key Laboratory of Bioinformatics, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China. Electronic address:
Glucagon is essential for glucose homeostasis, and its dysregulation is associated with diabetes. Despite extensive research, the mechanisms governing glucagon secretion remain incompletely understood. Here, we unveil that famsin, a gut-secreted hormone, promotes glucagon release and modulates glucose homeostasis.
View Article and Find Full Text PDFEur Geriatr Med
December 2024
Center for Sarcopenia and Malnutrition Research, Kumamoto Rehabilitation Hospital, 760 Magate, Kikuyo-Town, Kikuchi-County, Kumamoto, 869-1106, Japan.
Front Oncol
December 2024
Department of Geriatrics, Hematology & Oncology Ward, Guangzhou First People's Hospital, Guangdong Medical University, Guangzhou, Guangdong, China.
Hodgkin lymphoma variant of Richter syndrome (HL-type RS) is a very rare disease, in which chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) is transformed into novel Hodgkin lymphoma. The most important prognostic factor of HL-type RS is the clonal relationship between HL-type RS and the preexisting CLL/SLL. Detailed confirmation of clonally unrelated HL-type RS cases have not been reported.
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