Renshaw cells, corelease and nicotinic receptors: The last journey in synaptic transmission.

Philippe Ascher spent his last two decades as an emeritus Professor, working in the heart of Paris. Together with his wife Jacsue they were hosted in Alain Marty's laboratory and enjoyed the happiest retirement. We started our collaboration a few years after they started their retirement research at the Saint Pères campus where I was working on spinal motoneurons' physiology. This period led us from NMDA receptors to the corelease of acetylcholine and glutamate by spinal motoneurons to Renshaw cells and then to the stoichiometric variants of nicotinic acetylcholine receptors. Here I present a brief history of our collaboration during this period.