AI Article Synopsis
- The study presents a case series exploring an innovative endoscopic procedure, craniolateral inclinatory foraminotomy, which minimizes bone removal in patients with cervical radiculopathy undergoing multilevel decompression.
- Results showed significant clinical improvement in all 8 patients, with no reported complications like neck pain, instability, or lamina fractures, and good lamina preservation percentages across different cervical levels.
- The findings suggest that the new technique may enhance safety and effectiveness in treating cervical radiculopathy, while future technical refinements are expected to further reduce complications.
Article Abstract
Study Design: Case series.
Objective: Endoscopic posterior cervical foraminotomy gains attention for cervical radiculopathy due to its feasibility, better outcomes, and lower complications than traditional approaches, enabling efficient multilevel decompression in a single operation while avoiding anterior cervical diskectomy and fusion-related issues. However, with multilevel decompression, the remnant lamina becomes thin and fragile. We propose craniolateral inclinatory foraminotomy to minimize bone removal during laminotomy, reducing the risk of iatrogenic or postoperative lamina fractures in tandem decompression.
Materials And Methods: From 2021 to 2022, 8 consecutive patients underwent the procedure and were followed up for at least 6 months. The VAS, NDI, and MacNab scores were recorded for clinical recovery and patient satisfaction evaluations. Preoperative and postoperative CT scans were utilized to measure the lamina preservation percentage at each level.
Results: The clinical outcomes improved significantly in every patient. No postoperative neck pain, segmental instability, or lamina fracture were observed. The mean lamina preservation percentages of C5, C6, C7, and all vertebrae were 68.8%, 73.22%, 71.86%, and 72.18%, respectively.
Conclusions: Ongoing technical adjustments will accompany endoscopic technique development to decrease complications and enhance benefits. Our reported technique avoids extensive laminotomy in multilevel tandem decompression, aiming to prevent lamina fractures and anticipate a reduction in postoperative neck pain.
Level Of Evidence: Level IV.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/BSD.0000000000001722 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Rapid lightsheet fluorescence imaging of whole Drosophila brains at nanoscale resolution by potassium acrylate-based expansion microscopy.
Nat Commun
December 2024
Research Center for Applied Sciences, Academia Sinica, Taipei, 11529, Taiwan.
Taking advantage of the good mechanical strength of expanded Drosophila brains and to tackle their relatively large size that can complicate imaging, we apply potassium (poly)acrylate-based hydrogels for expansion microscopy (ExM), resulting in a 40x plus increased resolution of transgenic fluorescent proteins preserved by glutaraldehyde fixation in the nervous system. Large-volume ExM is realized by using an axicon-based Bessel lightsheet microscope, featuring gentle multi-color fluorophore excitation and intrinsic optical sectioning capability, enabling visualization of Tm5a neurites and L3 lamina neurons with photoreceptors in the optic lobe. We also image nanometer-sized dopaminergic neurons across the same intact iteratively expanded Drosophila brain, enabling us to measure the 3D expansion ratio.
View Article and Find Full Text PDFEstablishment of a 3D multi-layered in vitro model of inflammatory bowel disease.
J Control Release
January 2025
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal; IUCS-CESPU - Instituto Universitário de Ciências da Saúde, Rua Central de Gandra 1317, 4585-116 Gandra, Portugal. Electronic address:
Article Synopsis
- Crohn's Disease and Ulcerative Colitis are serious gastrointestinal disorders that currently have no cure, emphasizing the need for better research models to test new therapies.
- A new three-dimensional (3D) in vitro model mimics the IBD environment by incorporating multiple layers of tissue and immune responses, which includes human intestinal cells and macrophages.
- This innovative model allows for inducing inflammation similar to that seen in IBD, improving drug testing accuracy and potentially reducing reliance on animal studies while aiding in the understanding of disease mechanisms.
Mesoarchean Microbial Cd, Ba, and Ni Cycling: Evidence for Photosynthesis in Pongola Group Stromatolites through Novel Stable Isotopes and High-Resolution Trace Element Maps.
Astrobiology
December 2024
Department of Mineralogy, University of Hannover, Germany.
Nontraditional stable isotopes of bioactive metals emerged as novel proxies for reconstructing the biogeochemical cycling of metals, which serve as cofactors in major metabolic pathways. The fractionation of metal isotopes between ambient fluid and microorganisms is ultimately recorded in authigenic minerals, such as carbonates, which makes them potentially more reliable than standard biomarkers in organic matter. Stromatolitic carbonates are geochemical archives that allow for the study of the long-term interplay of the biosphere, atmosphere, and hydrosphere through deep time, with the unique potential to investigate early life environments and the evolution of the metallome.
View Article and Find Full Text PDFFibrinogen-Induced Regeneration Sealing Technique (F.I.R.S.T.): A Retrospective Clinical Study on 105 Implants with a 3-7-Year Follow-Up.
J Clin Med
November 2024
Department of Head and Neck Surgery and Maxillofacial Surgery, Tel-Aviv Sourasky Medical Center, School of Medicine, Tel Aviv University, 6 Weizmann Street, Tel-Aviv 6423906, Israel.
The primary aim of this retrospective clinical study was to assess the success and bone gain achieved by using the Fibrinogen-Induced Regeneration Sealing Technique (F.I.R.
View Article and Find Full Text PDFMaxilla of Siamopithecus eocaenus (Anthropoidea, Primates) from the Paleogene of Krabi, Thailand, and its taxonomic status.
J Hum Evol
January 2025
Laboratory Paleontology, Evolution, Paleoecosystems and Paleoprimatology (PALEVOPRIM), UMR 7262 CNRS, University of Poitiers, France.
Detailed descriptions of the maxillae of Siamopithecus eocaenus, discovered from the latest Eocene/earliest Oligocene lignite mine in the Krabi basin of Peninsular Thailand, are presented. They include the morphology of P-M, the palate, a partial orbital region, and the zygomatic root. The specimen exhibits distinctive dental features including a single-rooted P alveolus, a protocone on the P and P, and a true hypocone on the upper molars, indicating its derived anthropoid dentition.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!