AI Article Synopsis

  • - MASLD is a widespread chronic liver disease, affecting over 30% of people globally, and is primarily linked to metabolic issues like insulin resistance and type 2 diabetes.
  • - There is a significant two-way relationship between MASLD and diabetes, influencing each other's progression and treatment outcomes.
  • - Collaborative efforts from Taiwanese health organizations have led to new guidelines aimed at improving patient care for those with both diabetes and MASLD, focusing on surveillance and management strategies.

Article Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disease worldwide, affecting >30% of the global population. Metabolic dysregulation, particularly insulin resistance and its subsequent manifestation as type 2 diabetes mellitus, serves as the fundamental pathogenesis of metabolic liver disease. Clinical evidence of the recent nomenclature evolution is accumulating. The interaction and impacts are bidirectional between MASLD and diabetes in terms of disease course, risk, and prognosis. Therefore, there is an urgent need to highlight the multifaceted links between MASLD and diabetes for both hepatologists and diabetologists. The surveillance strategy, risk stratification of management, and current therapeutic achievements of metabolic liver disease remain the major pillars in a clinical care setting. Therefore, the Taiwan Association for the Study of the Liver (TASL), Taiwanese Association of Diabetes Educators, and Diabetes Association of the Republic of China (Taiwan) collaboratively completed the first guidance in patients with diabetes and MASLD, which provides practical recommendations for patient care.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11524742PMC
http://dx.doi.org/10.1097/HC9.0000000000000571DOI Listing

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