Histopathological examination holds a crucial role in cancer grading and serves as a significant reference for devising individualized patient treatment plans in clinical practice. Nevertheless, the distinctive features of numerous histopathological image targets frequently contribute to suboptimal segmentation performance. In this paper, we propose a UNet-based multi-scale context fusion algorithm for medical image segmentation, which extracts rich contextual information by extracting semantic information at different encoding stages and assigns different weights to the semantic information at different scales through TBSFF module to improve the learning ability of the network for features. Through multi-scale context fusion and feature selection networks, richer semantic features and detailed information are extracted. The target can be more accurately segmented without significantly increasing the extra overhead. The results demonstrate that our algorithm achieves superior Dice and IoU scores with a relatively small parameter count. Specifically, on the GlaS dataset, the Dice score is 90.56, and IoU is 83.47. For the MoNuSeg dataset, the Dice score is 79.07, and IoU is 65.98.
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http://dx.doi.org/10.1038/s41598-024-66585-x | DOI Listing |
Diagnostics (Basel)
January 2025
Department of Medical Device and Healthcare, Dongguk University, Seoul 04620, Republic of Korea.
Liver cancer has a high mortality rate worldwide, and clinicians segment liver vessels in CT images before surgical procedures. However, liver vessels have a complex structure, and the segmentation process is conducted manually, so it is time-consuming and labor-intensive. Consequently, it would be extremely useful to develop a deep learning-based automatic liver vessel segmentation method.
View Article and Find Full Text PDFFood Addit Contam Part A Chem Anal Control Expo Risk Assess
January 2025
UMR SayFood 0782, Université Paris-Saclay, INRAE, Palaiseau, AgroParisTech, France.
Assessing the contamination of paper and board (P&B) food packaging materials poses significant challenges due to the sensitivity limits of analytical methods and the low precision of sampling processes. This study aims to enhance the understanding of P&B food packaging contamination by investigating the distribution of contaminants at different scales using a combination of chromatographic and spectroscopic techniques. A total of 36 substances were targeted, including phthalates, photoinitiators, and bisphenol A.
View Article and Find Full Text PDFEntropy (Basel)
January 2025
School of Integrated Circuits and Electronics, Beijing Institute of Technology, Beijing 100081, China.
Optical Coherence Tomography (OCT) is a crucial imaging modality for diagnosing and monitoring retinal diseases. However, the accurate segmentation of fluid regions and lesions remains challenging due to noise, low contrast, and blurred edges in OCT images. Although feature modeling with wide or global receptive fields offers a feasible solution, it typically leads to significant computational overhead.
View Article and Find Full Text PDFSSM Popul Health
March 2025
Department of Education, Uppsala University, Uppsala, Sweden.
•Maternal relative deprivation is linked to intrauterine growth restriction.•Neighborhood income inequality is linked to fewer low Apgar scores in high-income mothers.•Findings support relative deprivation hypothesis over income inequality hypothesis.
View Article and Find Full Text PDFJ Struct Biol
January 2025
Shenzhen Bay Laboratory, Shenzhen 518132, China; Lingang Laboratory, Shanghai 200032, China. Electronic address:
Mitochondria are double membrane-bound organelles essential for generating energy in eukaryotic cells. Mitochondria can be readily visualized in 3D using Volume Electron Microscopy (vEM), and accurate image segmentation is vital for quantitative analysis of mitochondrial morphology and function. To address the challenge of segmenting small mitochondrial compartments in vEM images, we propose an automated mitochondrial segmentation method called GCTransNet.
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