Comprehending symmetry in epidemiology: A review of analytical methods and insights from models of COVID-19, Ebola, Dengue, and Monkeypox.

Medicine (Baltimore)

Department of Digital Anti-Aging Healthcare (BK21), Inje University Medical Big Data Research Center, Inje University, Gimhae, Republic of Korea.

Published: October 2024

AI Article Synopsis

  • Developing comprehensive mathematical models is vital for understanding infectious disease spread and guiding public health initiatives, but it's challenging due to past limitations like simulating population dynamics and reliable data collection.
  • The review highlights new diagnostic techniques for early virus detection and advances in modeling methods, including fractional calculus, which provides a more accurate representation of disease dynamics by accounting for memory effects.
  • It stresses the importance of ongoing funding for research and the need for innovative approaches to effectively translate complex model findings into practical public health strategies for future challenges.

Article Abstract

The challenge of developing comprehensive mathematical models for guiding public health initiatives in disease control is varied. Creating complex models is essential to understanding the mechanics of the spread of infectious diseases. We reviewed papers that synthesized various mathematical models and analytical methods applied in epidemiological studies with a focus on infectious diseases such as Severe Acute Respiratory Syndrome Coronavirus-2, Ebola, Dengue, and Monkeypox. We address past shortcomings, including difficulties in simulating population growth, treatment efficacy and data collection dependability. We recently came up with highly specific and cost-effective diagnostic techniques for early virus detection. This research includes stability analysis, geographical modeling, fractional calculus, new techniques, and validated solvers such as validating solver for parametric ordinary differential equation. The study examines the consequences of different models, equilibrium points, and stability through a thorough qualitative analysis, highlighting the reliability of fractional order derivatives in representing the dynamics of infectious diseases. Unlike standard integer-order approaches, fractional calculus captures the memory and hereditary aspects of disease processes, resulting in a more complex and realistic representation of disease dynamics. This study underlines the impact of public health measures and the critical importance of spatial modeling in detecting transmission zones and informing targeted interventions. The results highlight the need for ongoing financing for research, especially beyond the coronavirus, and address the difficulties in converting analytically complicated findings into practical public health recommendations. Overall, this review emphasizes that further research and innovation in these areas are crucial for addressing ongoing and future public health challenges.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11479419PMC
http://dx.doi.org/10.1097/MD.0000000000040063DOI Listing

Publication Analysis

Top Keywords

public health
16
infectious diseases
12
analytical methods
8
ebola dengue
8
dengue monkeypox
8
mathematical models
8
fractional calculus
8
models
5
comprehending symmetry
4
symmetry epidemiology
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!