Development of citric acid-based biomaterials for biomedical applications.

J Mater Chem B

Engineering Research Center for Biomedical Materials of Ministry of Education, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Material Science & Engineering, East China University of Science and Technology, Shanghai 200237, China.

Published: November 2024

AI Article Synopsis

  • - The study focuses on citric acid-based biomaterials, emphasizing their advantages like easy synthesis, adjustable properties, and compatibility with biological systems.
  • - It reviews the multifunctional aspects of these biomaterials, considering their physical, chemical, and biological properties.
  • - The paper highlights various applications of citrate-based biomaterials in biomedical engineering, including uses in bone and skin tissue engineering, drug delivery, and bioimaging.

Article Abstract

The development of bioactive materials with controllable preparation is of great significance for biomedical engineering. Citric acid-based biomaterials are one of the few bioactive materials with many advantages such as simple synthesis, controllable structure, biocompatibility, biomimetic viscoelastic mechanical behavior, controllable biodegradability, and further functionalization. In this paper, we review the development of multifunctional citrate-based biomaterials for biomedical applications, and summarize their multifunctional properties in terms of physical, chemical, and biological aspects, and finally the applications of citrate-based biomaterials in biomedical engineering, including bone tissue engineering, skin tissue engineering, drug/cell delivery, vascular and neural tissue engineering, and bioimaging.

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Source
http://dx.doi.org/10.1039/d4tb01666aDOI Listing

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