We consider the contextual bandit problem where at each time, the agent only has access to a noisy version of the context and the error variance (or an estimator of this variance). This setting is motivated by a wide range of applications where the true context for decision-making is unobserved, and only a prediction of the context by a potentially complex machine learning algorithm is available. When the context error is non-vanishing, classical bandit algorithms fail to achieve sublinear regret. We propose the first online algorithm in this setting with sublinear regret guarantees under mild conditions. The key idea is to extend the measurement error model in classical statistics to the online decision-making setting, which is nontrivial due to the policy being dependent on the noisy context observations. We further demonstrate the benefits of the proposed approach in simulation environments based on synthetic and real digital intervention datasets.
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Healthcare (Basel)
January 2025
School of Health Sciences, Polytechnic of Leiria, Rua General Norton de Matos, Apartado 4133, 2411-901 Leiria, Portugal.
Medication errors are the most frequent and critical issues in healthcare settings, often leading to worsened clinical outcomes, increased treatment costs, extended hospital stays, and heightened mortality and morbidity rates. These errors are particularly prevalent in intensive care units (ICUs), where the complexity and critical nature of the care elevate the risks. Nurses play a pivotal role in preventing medication errors and require strategies and methods to enhance patient safety.
View Article and Find Full Text PDFAlzheimers Res Ther
January 2025
Laboratory for Clinical Neuroscience, Center for Biomedical Technology, Universidad Politécnica de Madrid, IdISSC, Crta M40, km38, Madrid, 28223, Spain.
Background: Dementia patients commonly present multiple neuropathologies, worsening cognitive function, yet structural neuroimaging signatures of dementia have not been positioned in the context of combined pathology. In this study, we implemented an MRI voxel-based approach to explore combined and independent effects of dementia pathologies on grey and white matter structural changes.
Methods: In 91 amnestic dementia patients with post-mortem brain donation, grey matter density and white matter hyperintensity (WMH) burdens were obtained from pre-mortem MRI and analyzed in relation to Alzheimer's, vascular, Lewy body, TDP-43, and hippocampal sclerosis (HS) pathologies.
Sci Rep
January 2025
Department of Exercise Science, Syracuse University, 150 Crouse Dr, Syracuse, NY, 13244, USA.
Analyzing video footage of falls in older adults has emerged as an alternative to traditional lab studies. However, this approach is limited by the labor-intensive process of manually labeling body parts. To address this limitation, we aimed to validate the use of the AI-based pose estimation algorithm (OpenPose) in assessing the hip impact velocity and acceleration of video-captured falls.
View Article and Find Full Text PDFClin Chem Lab Med
January 2025
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Objectives: Careful consideration of the pre-analytical process for urine examination is essential to avoid errors and support accurate results and decision-making. Our objective was to assess the impact of various pre-analytical factors on urine test strip and quantitative chemistry results, including stability, tube type, fill volume, and centrifugation.
Methods: Residual random urine specimens were identified.
Poult Sci
January 2025
Hebei Agricultural University, Baoding, Hebei 071000, China; Key Laboratory of Intelligent Equipment and New Energy Utilization in Livestock and Poultry Farming of Hebei Province, Baoding, Hebei 071000, China.
At present, in the context of the highly intensive development of livestock and poultry breeding, digital management is becoming increasingly important, and digital twin systems are gradually being applied. To solve the contradiction between data acquisition and sensor network congestion, a virtual acquisition method based on historical data and real-time reference of point data is proposed when constructing a digital twin system. Firstly, computational fluid dynamics (CFD) simulation was used to analyze and determine the temperature distribution and environmental characteristics inside the layer house, and the collection area was preliminarily divided according to the CFD simulation results.
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