Catheter-directed thrombolysis reduces the thrombolytic time and dose of thrombolytic drugs without affecting the thrombolytic effect to ensure that bleeding does not occur. This helps clinicians choose safer CDT treatments for their patients. We combine the historical process of catheter-directed thrombolytic therapy for VTE and prospect the future development of CDT.
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Article Synopsis
- Acute pulmonary embolism (APE) has a high mortality rate, particularly due to right heart failure in intermediate to high-risk patients, with current guidelines advocating for thrombolytic therapy in high-risk cases.
- Despite the recommendations, thrombolytic therapy is not commonly used due to risks like intracranial hemorrhage, and there's still uncertainty about the best treatment for intermediate-risk patients.
- New endovascular interventions, such as various types of thrombolysis and mechanical thrombectomy, show promise in improving heart function and reducing bleeding risks, prompting future research to better identify patients who would benefit from these treatments and enhance long-term outcomes.
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