The Gulf Atlantic Coastal Plain (GACP) Long-Term Agroecosystem Research (LTAR) network site is characterized by hot and humid summers with low gradient stream channels surrounded by wetland forests and croplands. Beneath its sandy soils, a confining layer stifles recharge to the deeper aquifer system, so a substantial proportion of streamflow is driven by shallow subsurface baseflow. Agricultural practices in the area consist of forage and livestock production, forestry, and rotational cropping systems dominated by cotton (Gossypium hirsutum) and peanut (Arachis hypogaea). Certain factors impose challenges to the viability of GACP agricultural systems, like changing economics and demographics, as well as pest and disease pressures. The GACP communicates with stakeholders from various backgrounds, who provide their perspectives as agricultural research service scientists execute their research plans. The GACP LTAR common experiment (CE) is carried out via plot- and field-scale studies. The plot-scale CE compares prevailing practices, determined from regional data, with an alternative treatment including winter covers, such as the biofuel feedstock carinata (Brassica carinata, A. Braun), to provide both economic and environmental benefits. The field-scale CE is observational; key variables are monitored for two farms where management practices largely emulate the prevailing treatment. Data collection efforts quantify vegetation, hydrology, soils, and climate data to produce datasets for modeling and statistical analysis. Research teams quantify relationships between land management, environment, and socioeconomic benefits. Ultimately, the GACP LTAR site works to facilitate agricultural system health and wellbeing at local, regional, and national scales by providing long-term science-based solutions.
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http://dx.doi.org/10.1002/jeq2.20645 | DOI Listing |
SLAS Technol
December 2024
Center for Biomedical Engineering, School of Engineering, Brown University, Providence, RI 02912, USA. Electronic address:
Automated liquid handlers are fundamental in modern life science laboratories, yet their high costs and large footprints often limit accessibility for smaller labs. This study presents an innovative approach to decentralizing a liquid handling system by converting a low-cost 3D printer into a customizable and accurate liquid handler. The Personal Automated Liquid Handler (PALH) system, costing ∼$400, incorporates a single-channel pipet, custom 3D-printed components, and open-source software for personalized workflows, allowing researchers to build and modify the system for specific experimental needs.
View Article and Find Full Text PDFJ Colloid Interface Sci
December 2024
Department of Chemical, Materials and Production Engineering, University of Naples Federico II, Italy.
Hypothesis: Bubbles oscillating near a free surface are common across numerous systems. Thin liquid films (TLFs) formed between an oscillating bubble and a free surface can exhibit distinct morphological features influenced by interfacial properties, evaporation, and deformation history. We hypothesize that a continuous film presence throughout oscillation results in a wimple morphology, whereas intermittent film presence leads to a dimple formation.
View Article and Find Full Text PDFCell Rep
December 2024
Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:
The amino acid sequence of the T cell receptor (TCR) varies between T cells of an individual's immune system. Particular TCR residues nearly guarantee mucosal-associated invariant T (MAIT) and natural killer T (NKT) cell transcriptional fates. To define how the TCR sequence affects T cell fates, we analyze the paired αβTCR sequence and transcriptome of 961,531 single cells.
View Article and Find Full Text PDFPhytochem Anal
December 2024
Institute of Oncology, the First Clinical Medical College, Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Objectives: We used ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS), bioinformatics, and in vivo experiments to study the anti-colorectal cancer (CRC) effects of Wenzi Jiedu Decoction (WJD).
Methods: Detected the main components of WJD by UPLC-MS/MS. Obtained WJD targets and CRC targets through the open source database.
Mol Med
December 2024
Disease Prevention and Health Management Center, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310006, Zhejiang, China.
Background: Nonalcoholic fatty liver disease (NAFLD) has developed as a leading public wellness challenge as a result of changes in dietary patterns. Unfortunately, there is still a lack of effective pharmacotherapy methods for NAFLD. Wang's empirical formula (WSF) has demonstrated considerable clinical efficacy in treating metabolic disorders for years.
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