Magnetic nanoparticles: An emerging nanomedicine for cancer immunotherapy.

Prog Mol Biol Transl Sci

Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; Center for Translational Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. Electronic address:

Published: October 2024

Cancer immunotherapy is a revolutionised strategy that strikingly improves cancer treatment in recent years. However, like other therapeutic modalities, immunotherapy faces several challenges and limitations. Many methods have been developed to overcome those limitations; thus, nanomedicine is one of the emerging fields with a highly promising application. Magnetite nanoparticles (MNPs) have long been used for medical applications, for example, as a contrast medium, and are being investigated as a tool for boosting and synergizing the effects of immunotherapy. With known physicochemical properties and the interaction with the surroundings in biological systems, MNPs are used to improve the efficacy of immunotherapy in both cell-based and antibody-based treatment. This chapter reviews and discusses state-of-the-art MNPs as a tool to advance cancer immunotherapy as well as its limitations that need further investigation for a better therapeutic outcome in preclinical and clinical settings.

Download full-text PDF

Source
http://dx.doi.org/10.1016/bs.pmbts.2024.03.017DOI Listing

Publication Analysis

Top Keywords

cancer immunotherapy
12
immunotherapy
6
magnetic nanoparticles
4
nanoparticles emerging
4
emerging nanomedicine
4
cancer
4
nanomedicine cancer
4
immunotherapy cancer
4
immunotherapy revolutionised
4
revolutionised strategy
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!