First Detection and Characterization of in the Human Vagina in Two Sequential Samples over a Twelve-Day Interval.

Viruses

Laboratorio de Virologia (LIM52), Departamento de Infectologia e Medicina Tropical, Instituto de Medicina Tropical de São Paulo, Faculdade de Medicina da Universidade de São Paulo, Av. Dr Enéas de Carvalho Aguiar, 470, São Paulo 05403-000, Brazil.

Published: September 2024

AI Article Synopsis

  • A CRESS-DNA virus, primarily found in fecal samples from vertebrates, was examined in human vaginal samples for its presence.
  • Viral metagenomics was conducted on samples from 28 healthy women in NYC, with some providing duplicates over a 12-21 day span.
  • The study found that one individual had continuous detection of the CRESS-DNA virus over a twelve-day period, indicating it can persist in the human vagina.

Article Abstract

Background: is a CRESS-DNA virus identified almost exclusively in transient fecal samples from various vertebrate species.

Objective: We evaluated human vaginal samples for the presence and maintenance of .

Methods: Viral metagenomics analysis was performed on vaginal samples collected from 28 apparently healthy women in New York City, USA. Twenty-one of the women provided duplicate samples over a 12-21-day interval.

Results: Phylogenetic analysis identified two samples from the same individual, collected over a twelve-day interval, that were positive for the complete genome. All detected sequence contigs belonged to a single variant of CRESS-DNA.

Conclusions: The continuous presence of in the human vagina over a twelve-day period was identified.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11512292PMC
http://dx.doi.org/10.3390/v16101545DOI Listing

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