In this article, the relationship between the properties of different membranes (agar, chitosan, and agar + chitosan) and biodegradability in natural and sterilized soil was investigated. The membranes under investigation exhibited variations in the biodegradation process, a phenomenon closely linked to both the soil microbiota composition and their water affinity. Higher solubility in water and greater swelling tendencies correlated with shorter initiation times for the biodegradation process in soil. Overall, all tested membranes began biodegradation within 14 days, as assessed through thickness and morphological analysis parameters, demonstrating a superior degradation rate compared to low-density polyethylene films.
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http://dx.doi.org/10.3390/polym16202940 | DOI Listing |
Ann Pharm Fr
December 2024
College of Pharmacy, National University of Science and Technology, Muscat, Oman.
Implantable drug delivery systems offer numerous benefits, including effective drug administration at lower concentrations, fewer side effects, and improved patient compliance. Various polymers are used for fabricating implants, with biopolymers, particularly polysaccharides, being notable for their ability to modulate drug delivery characteristics. The review aims to describe the strategies employed in the development of polysaccharide-based implants and provide a comprehensive understanding of various polysaccharides such as starch, cellulose, alginate, chitosan, pullulan, carrageenan, dextran, hyaluronic acid, agar, pectin, and gellan gum in the fabrication of implant for targeted therapy.
View Article and Find Full Text PDFBiopolymers
January 2025
Marine Biotechnology, National Institute of Ocean Technology, Ministry of Earth Sciences, Govt. of India, Chennai, India.
ChemistryOpen
November 2024
Institute for Tropical Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Cau Giay, Hanoi, 100000, Vietnam.
Dent Res J (Isfahan)
October 2024
Department of Pediatric Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: This study aimed to assess the antibacterial effect of a nano-zinc oxide eugenol (nZOE) sealer alone and in combination with chitosan, propolis, and nanosilver on .
Materials And Methods: In this , experimental study, nanosilver, chitosan, and propolis with 10wt%, 20wt%, and 60wt% concentrations, respectively, were added to nZOE sealer, and their antibacterial activity against was evaluated by agar diffusion and broth microdilution tests. The diameter of the growth inhibition zones was measured, and the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values were calculated for all materials.
Int J Biol Macromol
December 2024
Department of Chemistry, University of Kerala, Kariavattom, Thiruvananthapuram 695581, Kerala, India. Electronic address:
Self-assembled hydrogels derived from naturally sourced polymers have gained significant interest in drug delivery applications, owing to their potential, exceptional biocompatibility and sustainable properties. This work presents the development and application of self-assembled nanocomposite hydrogels from chitosan and nanosilver as a pH responsive drug delivery system for the controlled release of doxorubicin and paclitaxel in anticancer therapy. Chitosan was functionalized with 4-formyl benzoic acid for incorporating both hydrophobic and hydrophilic anticancer drugs.
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