The notch effect of semicrystalline PVDF was investigated using U- and V-notch geometries with different depths, and tensile tests were performed at 23 °C using the DIC technique and FEA. Both unnotched and notched dumbbell-shaped specimens were subjected to tensile loading with the DIC technique to obtain mechanical curves and strain maps. The experimental data were compared to a numerical model, analyzing both global mechanical curves and local strain maps around the notch region to assess the accuracy of the simulations. The results demonstrated that the geometry and depth of the notch influence the mechanical behavior of PVDF, presenting a decrease in load and displacement compared to unnotched specimens. This aspect was corroborated by strain maps, which showed the increase in the local strain around the notch tip. For FEA, the global analysis indicated a good correlation with experimental results, and the local analysis demonstrated a reasonable agreement in strain map results within 0.5 mm of the notch neighborhood. Overall, the DIC technique and FEA provided a reliable evaluation of notch behavior on the PVDF used as pressure sheaths with reasonable precision.
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http://dx.doi.org/10.3390/polym16202906 | DOI Listing |
Accid Anal Prev
December 2024
Zachry Department of Civil & Environmental Engineering, Texas A&M University, College Station, TX 77843, USA.
Near-miss traffic risk estimation using Extreme Value Theory (EVT) models within a real-time framework offers a promising alternative to traditional historical crash-based methods. However, current approaches often lack comprehensive analysis that integrates diverse roadway geometries, crash patterns, and two-dimensional (2D) vehicle dynamics, limiting both their accuracy and generalizability. This study addresses these gaps by employing a high-fidelity, 2D time-to-collision (TTC) near-miss indicator derived from autonomous vehicle (AV) sensor data.
View Article and Find Full Text PDFCardiovasc Ther
January 2025
Department of Cardiothoracic Surgery, Ningbo Medical Center Lihuili Hospital of Ningbo University, No. 57, Xingning Rd, Ningbo City 315041, Zhejiang Province, China.
Doxorubicin (DOX) is a widely used antitumor drug; however, its use is limited by the risk of serious cardiotoxicity. Dehydroevodiamine (DHE) is a quinazoline alkaloid which has antiarrhythmic effects. The aim of this study was to investigate the protective effect of DHE on doxorubicin-induced cardiotoxicity (DIC) and its potential mechanism.
View Article and Find Full Text PDFPLoS One
December 2024
Department of Earth and Environmental Sciences, Vanderbilt University, Nashville, Tennessee, United States of America.
Monitoring the seasonal and diurnal variations in headwater stream metabolic regimes can provide critical information for understanding how ecosystems will respond to future environmental changes. In East Fork Creek, a headwater stream in middle Tennessee, week-long field campaigns were set up each month from May 2022 to May 2023 to collect stream metabolism estimators. In a more extensive field campaign from July 2-5 in 2022, diel signals were observed for temperature, pH, turbidity, and concentrations of Ca, Mg, K, Se, Fe, Ba, chloride, nitrate, DIC, DO, DOC, and total algae.
View Article and Find Full Text PDFArch Razi Inst
June 2024
Hepatitis Research Center, Department of Virology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.
Human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) are known as the most common blood-borne viral infections worldwide. Individuals referring to drop-in centers (DICs) are considered high-risk people exposed to infection with blood-borne viruses. The purpose of this study was to investigate the prevalence of HIV, HBV, and HCV infections among women referred to DICs in Lorestan Province, western Iran.
View Article and Find Full Text PDFBMC Cancer
December 2024
Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Background: The complexity of acute myeloid leukemia (AML) is increasingly recognized through the identification of distinct subgroups, including those with an APL-like immunophenotype characterized by the absence of CD34 and HLA-DR expression, which is widely recognized as a representative immunophenotype in acute promyelocytic leukemia (APL). This study sought to understand the clinical, molecular, and prognostic differences between AML patients with and without this phenotype.
Methods: This study retrospectively analysed 191 de novo non-M3 AML patients and identified 32 patients with the CD34HLA-DR phenotype resembling APL-like immunophenotype, considered as the experimental group.
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