AI Article Synopsis

  • Esophageal anastomotic fistula (AF) is a common and serious complication after esophagectomy for cancer, typically managed with endoscopic stents.
  • A study analyzed data from 55 patients with AF to investigate healing times and factors affecting them, focusing on hospital stays and stent usage until the fistula closed.
  • Findings revealed that different anastomosis types affected healing durations, with eso-gastric anastomosis patients experiencing longer hospital stays and eso-gastric cervical anastomosis showing prolonged fistula closure, particularly influenced by fistula size and prior radiotherapy treatments.

Article Abstract

Esophageal anastomotic fistula (AF) is a frequent and severe complication of an esophagectomy due to esophageal or eso-gastric junction cancer, regardless of the selected surgical technique. AF is usually treated by endoscopic stent placement. : This study aims to examine the efficacy of stents in the treatment of AF, analyzing the healing period and the factors that contribute to its delay. : We collected data from 55 patients who underwent stent implantation for AF, and analyzed multiple variables related to patient healing time and surgical technique with two primary endpoints: post-stenting hospital stay and the time of stent usage until fistula closure. The patients were divided into three groups based on the anastomosis type (eso-gastric anastomosis, eso-gastric cervical anastomosis and eso-jejunal anastomosis) and they were compared using the primary endpoints. : Our findings show the differences between the three groups, with a longer hospital stay for eso-gastric anastomosis, and an extended time of fistula closure in the case of eso-gastric cervical anastomosis. We also found a significant correlation between the size of the fistula and the hospital stay (R = 0.4, < 0.01). Regarding patients' risk factors, our results show an extended post-stenting hospital stay for those patients that underwent preoperative radiotherapy. : Our results offer an extended view of the efficiency, hospitalization duration and healing time for esophageal anastomotic fistula, and reveal some of the factors that interfere with its resolution.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11508254PMC
http://dx.doi.org/10.3390/jcm13206167DOI Listing

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