AI Article Synopsis
- * Many cases of HCC are diagnosed inoperable, necessitating alternative treatment options beyond surgery, despite some cases being treatable through surgical resection or transplantation.
- * This review focuses on key locoregional therapies for HCC in NAFLD patients, such as transarterial chemoembolization (TACE), bland transarterial embolization (TAE), trans
Article Abstract
Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death worldwide with an average five-year survival rate in the US of 19.6%. With the advent of HBV and HCV treatment and prevention, along with the rising rates of obesity, nonalcoholic fatty liver disease (NAFLD) and metabolic syndrome are set to overtake infectious causes as the most common cause of HCC. While surgical resection and transplantation can be curative when amenable, the disease is most commonly unresectable on presentation, and other treatment approaches are the mainstay of therapy. In these patients, locoregional therapies have evolved as a vital tool in both palliation for advanced disease and as a bridge to surgical resection and transplantation. In this review, we will be exploring the primary locoregional therapies for HCC in patients with NAFLD, including transarterial chemoembolization (TACE), bland transarterial embolization (TAE), transarterial radioembolization (TARE), and percutaneous ablation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11504147 | PMC |
| http://dx.doi.org/10.3390/biomedicines12102226 | DOI Listing |
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