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All-optical optoacoustics for clinical diagnostics.
Nat Biomed Eng
October 2024
Institute for Biomedical Engineering and Institute of Pharmacology and Toxicology, Faculty of Medicine, University of Zürich, Zürich, Switzerland.
An optoacoustic field-programmable perceptron for recurrent neural networks.
Nat Commun
April 2024
Max Planck Institute for the Science of Light, Staudtstr. 2, 91058, Erlangen, Germany.
Recurrent neural networks (RNNs) can process contextual information such as time series signals and language. But their tracking of internal states is a limiting factor, motivating research on analog implementations in photonics. While photonic unidirectional feedforward neural networks (NNs) have demonstrated big leaps, bi-directional optical RNNs present a challenge: the need for a short-term memory that (i) programmable and coherently computes optical inputs, (ii) minimizes added noise, and (iii) allows scalability.
View Article and Find Full Text PDFArticle Synopsis
- - Ultrasound coupling is a major challenge in using traditional photoacoustic microscopy (PAM) for clinical examination of chronic wounds.
- - Photoacoustic remote sensing (PARS) is a promising solution that utilizes all-optical measurements and has shown potential in functional imaging of tissue but needs further exploration in hemodynamic quantification.
- - The study introduces an all-optical thermal-tagging flowmetry method for PARS Microscopy, demonstrating its effectiveness with high accuracy in measuring blood flow rates from 0 to 12 mm/s without using dyes.
All-optical optoacoustic micro-tomography in reflection mode.
Biomed Eng Lett
August 2023
Andrew and Erna Viterbi Faculty of Electrical & Computer Engineering, Technion - Israel Institute of Technology, Technion City, Haifa, 32000 Israel.
High-resolution optoacoustic imaging at depths beyond the optical diffusion limit is conventionally performed using a microscopy setup where a strongly focused ultrasound transducer samples the image object point-by-point. Although recent advancements in miniaturized ultrasound detectors enables one to achieve microscopic resolution with an unfocused detector in a tomographic configuration, such an approach requires illuminating the entire object, leading to an inefficient use of the optical power, and imposing a trans-illumination configuration that is limited to thin objects. We developed an optoacoustic micro-tomography system in an epi-illumination configuration, in which the illumination is scanned with the detector.
View Article and Find Full Text PDFGigahertz optoacoustic vibration in Sub-5 nm tip-supported nano-optomechanical metasurface.
Nat Commun
January 2023
College of Physical Science and Technology, Xiamen University, Xiamen, China.
The gigahertz acoustic vibration of nano-optomechanical systems plays an indispensable role in all-optical manipulation of light, quantum control of mechanical modes, on-chip data processing, and optomechanical sensing. However, the high optical, thermal, and mechanical energy losses severely limit the development of nano-optomechanical metasurfaces. Here, we demonstrated a high-quality 5 GHz optoacoustic vibration and ultrafast optomechanical all-optical manipulation in a sub-5 nm tip-supported nano-optomechanical metasurface (TSNOMS).
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