AI Article Synopsis
- * The generated iPSCs maintained a normal karyotype and expressed pluripotency markers, indicating their potential.
- * These iPSCs demonstrated the ability to differentiate into all three germ layers in vitro, paving the way for future research applications.
Article Abstract
We isolated peripheral blood mononuclear cells (PBMCs) from a healthy female donor, and successfully converted into induced pluripotent stem cells (iPSCs) by using non-integrating episomal vectors. These iPSCs displayed a normal karyotype, expressed markers of pluripotency, and showed the capacity to differentiate into three germ layers in vitro, which could be utilized for future research endeavors.
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| http://dx.doi.org/10.1016/j.scr.2024.103590 | DOI Listing |
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