AI Article Synopsis

  • This text reports a unique case of chronic post-operative endophthalmitis (CPOE) after routine eye surgery, with a gram-positive bacterium identified as the cause.
  • The case involves a 64-year-old man who experienced recurring eye inflammation over six years, initially misdiagnosed but later confirmed through positive vitreous culture.
  • Successful treatment required surgical intervention, including vitrectomy and IOL removal, though the patient suffered vision loss from secondary glaucoma.

Article Abstract

Purpose: To report the first case of ocular infection manifesting as chronic post-operative endophthalmitis (CPOE) following routine phacoemulsification with intraocular lens (IOL) implantation. This gram-positive bacterium is recognised as a cause of hardware infections in immunocompetent hosts, such as prosthetic cardiac valves, ventriculoperitoneal shunts, and orthopaedic hardware, often necessitating surgical removal of the infected prostheses for cure.

Methods: Case report and literature review.

Results: A 64-year-old male with a history of uncomplicated cataract extraction and IOL insertion had multiple presentations over 6 years, with relapsing-remitting intraocular inflammation with multiple negative vitreous cultures treated as non-infectious panuveitis. An eventual positive vitreous culture for led to a diagnosis of CPOE, which was successfully treated with vitrectomy, removal of IOL, and intravitreal vancomycin injections. However, advanced vision loss occurred due to secondary glaucoma.

Conclusion: is a novel cause of CPOE, which is typically attributed to other low virulence organisms. As with infections of non-ocular implanted hardware by , surgical removal of the infected IOL-capsule complex was required for cure. The CPOE diagnosis requires a combination of high index of suspicion and culture of vitreous and capsular material. The role of IOL removal for the treatment of CPOE is discussed.

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Source
http://dx.doi.org/10.1080/09273948.2024.2417799DOI Listing

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