Crimean-Congo Hemorrhagic Fever (CCHF) presents significant global health challenges, highlighted by its sporadic nature and high fatality rates. The manuscript emphasizes the disease's tendency to be under-recognized and the diagnostic challenges it poses, often mimicking other illnesses and leading to frequent misdiagnosis. There is a noted absence of robust diagnostic tools, specific treatments, or vaccines, leaving only supportive care generally available. The necessity for increased international cooperation and a coordinated strategy to enhance disease surveillance, public health preparedness, and community education is stressed.
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http://dx.doi.org/10.1080/23744235.2024.2420253 | DOI Listing |
Int Med Case Rep J
January 2025
Department of Oral Medicine, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia.
Introduction: Opportunistic infections (IO) are infections of microbiota (fungi, viruses, bacteria, or parasites) that generally do not cause disease but turn into pathogens when the body's defense system is compromised. This can be triggered by various factors, one of which is due to a weakened immune system due to Diabetes Mellitus (DM), which increases the occurrence of opportunistic infections, especially in the oral cavity. Fungal (oral candidiasis) and viral (recurrent intraoral herpes) infections can occur in the oral cavity of DM patients.
View Article and Find Full Text PDFFront Antibiot
February 2024
School of Biosciences & Institute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom.
Antimicrobial resistance is a growing public health concern, increasingly recognized as a silent pandemic across the globe. Therefore, it is important to monitor all factors that could contribute to the emergence, maintenance and spread of antimicrobial resistance. Environmental antibiotic pollution is thought to be one of the contributing factors.
View Article and Find Full Text PDFEcol Evol
January 2025
Department of Environmental Systems Science ETH Zürich Switzerland.
Scavenging is a widespread feeding strategy involving a diversity of taxa from different trophic levels, from apex predators to obligate scavengers. Scavenger species play a crucial role in ecosystem functioning by removing carcasses, recycling nutrients and preventing disease spread. Understanding the trophic roles of scavenger species can help identify specialized species with unique roles and species that may be more vulnerable to ecological changes.
View Article and Find Full Text PDFInt J Surg Case Rep
January 2025
Department of Thoracic Surgery, Al-Ahli Hospital, Hebron, Palestine; Department of Medicine, Faculty of Medicine and Health Sciences, Al-Quds University, Jerusalem, Palestine.
Introduction And Importance: Pulmonary lymphangitis carcinomatosis (PLC) is a rare and aggressive condition that silently spreads cancer cells through the lungs' lymphatic system. Often linked to advanced malignancies, PLC often mimics other pulmonary diseases, making diagnosis challenging. This report shares the unique case of an asymptomatic patient whose routine follow-up imaging led to the early discovery of PLC, highlighting the life-saving potential of attentive medical care.
View Article and Find Full Text PDFbioRxiv
December 2024
Department of Biochemistry and Molecular Genetics, University of Colorado, Denver - Anschutz Medical Campus.
Organisms with smaller genomes often perform multiple functions using one multi-subunit protein complex. The Silent Information Regulator complex (SIRc) carries out all of the core functions of heterochromatin. SIR complexes first drive the initiation and spreading of histone deacetylation in an iterative manner.
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