AI Article Synopsis

  • - Medication adherence is crucial for effective treatment in chronic diseases, particularly cardiovascular diseases (CVDs), and this study aimed to assess adherence using both subjective (self-reported surveys) and objective (pill counting) methods among outpatients from Fukuoka University Chikushi Hospital.
  • - The study involved 94 patients and found no significant differences in adherence when comparing subjective survey scores with objective pill counting results, highlighting a discrepancy between how patients perceive their adherence and actual medication-taking behavior.
  • - A multivariate analysis identified obesity as a significant factor linked to poor medication adherence, suggesting that healthcare providers should pay extra attention to patients with CVD who are also obese.

Article Abstract

Medication adherence is important for the appropriate drug-based treatment in patients with chronic diseases, especially those with cardiovascular diseases (CVDs). The purpose of the present study was to evaluate medication adherence among patients with CVDs using subjective and objective measurements. We enrolled outpatients who visited Fukuoka University Chikushi Hospital from June to December 2022. As a subjective measurement, we used a self-reported questionnaire developed by Ueno et al., which consists of 12 questionnaire items grouped into the following four domains: medication compliance (subjective compliance), collaboration with health care providers (collaboration), willingness to access and use information about medication (willingness), and acceptance to take medication and how taking medication fits a patient's lifestyle (acceptance). The pill counting method was used as an objective measurement to calculate the medication adherence rate; Poor Adherence was defined as a medication adherence rate of <100%. Ninety-four patients were analyzed. No statistically significant differences were observed between the patients in the Good and Poor Adherence groups classified by pill counting, an objective indicator; in the subjective evaluation index Ueno scale scores of subjective compliance, collaboration, willingness, and acceptance domains; and in the total score. A multivariate analysis revealed that obesity (odds ratio, 3.527; 95% confidence interval, 1.387-9.423; = 0.008) was an independent factor associated with Poor Adherence. In conclusion, we found a discrepancy between subjective and objective measurements for the evaluation of medication adherence. Furthermore, obesity was an independent factor associated with poor medication adherence assessed by the pill counting method; thus, patients with CVD and obesity require a careful follow-up.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11511389PMC
http://dx.doi.org/10.3390/pharmacy12050153DOI Listing

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