AI Article Synopsis
- Hydroxyapatite (HA) is a key component of human teeth and bones, valuable for its bioactivity and ability to support bone growth, making it suitable for use as an implant coating in dental and maxillofacial surgeries.
- However, its low fracture toughness and brittleness limit HA's use in areas subjected to heavy stress.
- Research into substituting HA with external ions shows potential for enhancing its properties, leading to improved remineralization, antimicrobial activity, and hardness, indicating a promising direction for future dental materials and therapies.
Article Abstract
Hydroxyapatite (HA) forms an essential constituent of human teeth and bone. Its distinctive characteristic features, such as bioactivity and osteoconductivity, make it an ideal candidate to be used as an implant coating in restorative dentistry and maxillofacial surgery for bone regeneration. However, low fracture toughness and brittleness are a few of the inherent features of HA, which limit its application in load-bearing areas. The potential of HA to engage its lattice structure with either partial or complete substitution with external ions has become an increasing area of research as this phenomenon has the potential to enhance the biological and functional properties of the material. Consequently, this review aimed to highlight the role of various substituted ions in dental applications. Data indicate that the newly formed HA-substituted biomaterials demonstrate enhanced remineralization and antimicrobial activity along with improved hardness. Ion-substituted HA offers a promising strategy for future clinical research as these materials may be incorporated into various dental products for therapeutic treatments.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11506108 | PMC |
| http://dx.doi.org/10.3390/dj12100304 | DOI Listing |
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