Multi-Cancer Early Detection is a highly popular topic, bringing the hope of being able to detect very early, non-symptomatic cancers and allowing more successful therapy. A major company in this space is GRAIL, which has attracted very significant financing and launched large-scale tests of its detection systems. However, the real clinical utility of these tests remains to be demonstrated, and fundamental issues are still pending.
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http://dx.doi.org/10.1051/medsci/2024107 | DOI Listing |
Afr J AIDS Res
December 2024
For TB HIV CARE, Cape Town South Africa. For Harry Hausler's affiliation: Department of Family Medicine, University of Pretoria.
This paper focused on the prevention of HIV transmission for adolescent girls and young women (AGYW), through a layered approach which included economic strengthening as a core strategy, especially for the most vulnerable. Based on multi-year data in KwaZulu-Natal, South Africa, we assessed the outcomes of an economic strengthening model developed by TB HIV Care (THC) in the Determined, Resilient, Empowered, AIDS-free, Mentored and Safe (DREAMS) HIV prevention programme. The methods used are primarily qualitative.
View Article and Find Full Text PDFEur J Transl Myol
December 2024
ENT-Department, Facial-Nerve-Center and Center of Rare Diseases, Jena University Hospital, Jena.
Mega scientific conferences increasingly suffer from the need for short and poster presentations without discussion. An alternative is to organize workshops in hotels large enough to accommodate all participants. This significantly increases the opportunities for constructive discussion during breakfasts, lunches, dinners and long evenings that can bring together experts of scientific and clinical sub-specialties and young fellows.
View Article and Find Full Text PDFCrit Care
November 2024
Biostatistics Unit, Department of Clinical Research and Innovation (DRCI), CHU Clermont-Ferrand, Clermont-Ferrand, France.
Background: Postextubation respiratory failure (PRF) frequently complicates weaning from mechanical ventilation and may increase morbidity/mortality. Noninvasive ventilation (NIV) alternating with high-flow nasal oxygen (HFNO) may prevent PRF.
Methods: Ventilated patients without chronic obstructive pulmonary disease (COPD) and at high-risk of PRF defined as a lung ultrasound score (LUS) ≥ 14 assessed during the spontaneous breathing trial, were included in a French-Chinese randomised controlled trial.
Cureus
October 2024
Department of Pediatric and Preventive Dentistry, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, IND.
This biography of Sigmund Freud examines the life and contributions of the individual recognized as the progenitor of psychoanalysis, analyzing his significant influence on the fields of psychology, culture, and the comprehension of the human psyche. Sigmund Freud was born in 1856 in Freiburg, Moravia. His early education and burgeoning interest in the field of medicine established a critical foundation for the development of his innovative theories.
View Article and Find Full Text PDFBehav Sleep Med
January 2025
Department of Psychiatry, University of Rochester Medical Center, Rochester, NY, USA.
Objectives: This study aimed to investigate relationships between lucid dreaming and sleep and mental health outcomes within a representative sample of the general population. We also sought to examine how nightmares interact with the relationship between lucid dreaming, sleep, and mental health outcomes.
Methods: Participants ( = 1332) completed measures of lucid dream frequency, nightmare frequency, anxiety and depressive symptoms, stress, and sleep quality.
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