Background: Diabetes Mellitus coexisting with hypertension has received significant global attention and remains a public health challenge in the past two decades. The states of hyperinsulinemia and insulin resistance have been postulated as causes or consequences of hypertension. Evidence shows that alternative systems of medicine can play a significant role in achieving glycemic control. This study aimed to compare and evaluate the impact of yoga and naturopathy-based lifestyles on patients with diabetes mellitus and diabetes mellitus with hypertension.
Methods: Sixty subjects were recruited into two groups, group 1 (diabetes mellitus with hypertension) and group 2 (diabetes mellitus) based on the inclusion and exclusion criteria. Both the groups underwent naturopathy and yoga intervention for ten days. The glycemic profile and heart rate variability (HRV) of the patients were assessed at the baseline and 10 days after the intervention.
Results: Study resulted in a significant change in both time domain and frequency domain variables (HRV, FBS, and PPBS) in both group 1 and group 2 (P < .05, for all) but the mean difference was more in group 2 with a significant difference between the two groups, P < .05. The diastolic blood pressure significantly decreased only in group 2, whereas the systolic blood pressure decreased in both groups without any difference between the two groups.
Conclusion: The results of the present study show that integrated yoga and naturopathy management significantly help in glycemic control and autonomic functions in both groups.
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Diabetes Metab Res Rev
January 2025
Department of Human Genetics, Guru Nanak Dev University, Amritsar, India.
Aim: This review explores the increasing prevalence of Type 2 Diabetes Mellitus (T2DM) in children and adolescents, focusing on its etiology, risk factors, complications, and the importance of early detection and management. It also highlights the need for a multidisciplinary, family-centered approach in managing T2DM in pediatric populations, with an emphasis on nutrition, exercise, and lifestyle interventions.
Materials And Methods: A literature review was conducted using PubMed, Google Scholar, and Scopus to incorporate studies from 2015 to 2024 on T2DM in youths/adolescents/children, focusing on epidemiology, risk factors, and prevention strategies.
Chembiochem
January 2025
Nankai University, Institute of Polymer Chemistry, CHINA.
Diabetes is a metabolic disorder characterized by insufficient endogenous insulin production or impaired sensitivity to insulin. In recent years, a class of incretin-based hypoglycemic drugs, glucagon-like peptide-1 receptor agonists (GLP-1RAs), have attracted great attention in the management of type 2 diabetes mellitus (T2DM) due to their benefits, including stable glycemic control ability, a low risk of hypoglycemia, and weight reduction for patients. However, like other peptide drugs, GLP-1RAs face challenges such as instability, susceptibility to enzymatic degradation, and immunogenicity, which severely limit their clinical application.
View Article and Find Full Text PDFActa Obstet Gynecol Scand
January 2025
Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada.
Introduction: Evidence suggests that gestational diabetes mellitus (GDM) is associated with subsequent cardiovascular disease; however, it is unclear what impact changes in screening and diagnostic criteria have had on the association of GDM with long-term outcomes such as cardiovascular disease. The purpose of this study was to determine the association between GDM and subsequent cardiovascular disease during a period of rising gestational diabetes diagnosis in England. Specifically, associations were compared before and after 2008, when national guidelines supporting risk factor-based screening were introduced.
View Article and Find Full Text PDFInt J Clin Pharmacol Ther
December 2024
Objectives: We aimed to study sarcopenia for its significance in predicting the effect of hepatic artery intervention (HAI) plus lenvatinib on hepatitis B-related hepatocellular carcinoma (HCC) complicated with diabetes mellitus (DM).
Materials And Methods: Hepatitis B-related HCC patients complicated with DM (n = 102) visiting during January 2021 and December 2023 were retrospectively selected. Computed tomography was performed to detect the third lumbar vertebra for its muscle cross-sectional area.
Introduction: Free radical-mediated oxidative renal tubular injury secondary to hyperoxaluria is a proposed mechanism in the formation of calcium oxalate stones. Vitamin E, an important physiologic antioxidant, has been shown in rat models to prevent calcium oxalate crystal deposition. Our objective was to determine if low dietary vitamin E intake was associated with a higher incidence of stones.
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