When evaluating soft self-assembling materials for use in any application, the structural or morphological characterisation is highly important. We know that the hierarchal molecular self-assembly of these materials into larger structures directly influences behaviours such as performance and stability. It is therefore imperative that these materials are characterised effectively over multiple length scales. Two effective methods of achieving this are small angle scattering (SAS) and imaging. Scattering giving us indirect information about the systems, whereas imaging is often looking at the material directly. In this review, we discuss the benefits, caveats and power of using both these techniques separately and together for the characterisation of supramolecular gels.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496719PMC
http://dx.doi.org/10.3762/bjoc.20.220DOI Listing

Publication Analysis

Top Keywords

small angle
8
angle scattering
8
characterisation supramolecular
8
supramolecular gels
8
applications microscopy
4
microscopy small
4
scattering techniques
4
techniques characterisation
4
gels evaluating
4
evaluating soft
4

Similar Publications

Maintaining hexagonal structures through interfacial positioning of crosslinkers for nanofiltration.

J Colloid Interface Sci

December 2024

Institute for Frontier Materials, Deakin University, Geelong VIC 3216, Australia. Electronic address:

Hypothesis: Optimizing interfacial positioning of crosslinkers within a reactive self-assembled hexagonal lyotropic liquid crystals (HLLC) system could assist in retaining the hexagonal structure during polymerization and thereby improving water filtration performances of the as-synthesized nanofiltration membranes.

Experiments: The positioning of the hydrophilic crosslinker, poly (ethylene glycol) diacrylate (PEGDA), within the reactive HLLC system was systematically investigated using H and C solid nuclear magnetic resonance (NMR) and small angle X-ray scattering (SAXS) techniques. The structural variation and water filtration performances of these HLLC systems with/without crosslinkers after polymerization were further studied using grazing incidence SAXS (GISAXS) and crossflow filtration tests, respectively.

View Article and Find Full Text PDF

Relative anterior microphthalmos (RAM) is a rare ocular condition characterized by disproportionately small anterior segments but normal axial length (corneal diameter < 11 mm and axial length > 20 mm). This study aimed to determine the prevalence of RAM and its association with glaucoma utilizing IOL Master 700 data (Carl Zeiss Meditec, Jena, Germany). A retrospective analysis was conducted of the biometric parameters of 6,407 eyes, and 115 cases of RAM were identified.

View Article and Find Full Text PDF

Towards a better knowledge of U(VI) speciation in weakly alkaline solution through an in-depth study of U(VI) intrinsic colloids.

Chemosphere

December 2024

Institut de Chimie Séparative de Marcoule, CEA, UMR 5257 CEA-CNRS-UM-ENSCM, 30207 Bagnols-sur-Cèze, France. Electronic address:

The formation of U(VI) intrinsic colloids has a non-negligible impact on the dissemination of actinides in the environment. It is therefore essential to better identify their nature, formation conditions, and stability domains. These specific points are especially important since the behavior of these elements in environment is generally estimated by geochemical transport modeling.

View Article and Find Full Text PDF

Hypothesis: Nanoscale characterisation of the self-associated species formed by amphiphilic pharmaceuticals in aqueous solution carries relevance across their entire journey from development through to manufacture - relevant, therefore, not only as regards formulation of the drug products as medicines, but also potentially relevant to their bioavailability, activity, and clinical side effects. Such knowledge and understanding, however, can only be fully secured by applying a range of experimental and theoretical methodologies.

Experiments: Herein, we apply a synergistic combination of solubility, surface tension, SANS, NMR and UV spectroscopic studies, together with MD simulation and QM calculations, to investigate the meso-structures of propranolol hydrochloride aggregates in bulk aqueous solutions, at concentrations spanning 2.

View Article and Find Full Text PDF

Ionic Crosslinking of Linear Polyethyleneimine Hydrogels with Tripolyphosphate.

Gels

December 2024

Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Ciencias Químicas, Ciudad Autónoma de Buenos Aires 1113, Argentina.

In this work, the mechanical properties of hydrogels based on linear polyethyleneimine (PEI) chemically crosslinked with ethyleneglycoldiglycidyl ether (EGDE) were improved by the ionic crosslinking with sodium tripolyphosphate (TPP). To this end, the quaternization of the nitrogen atoms present in the PEI structure was conducted to render a network with a permanent positive charge to interact with the negative charges of TPP. The co-crosslinking process was studied by H high-resolution magic angle spinning (H HRMAS) NMR and X-ray photoelectron spectroscopy (XPS) in combination with organic elemental analysis and inductively coupled plasma mass spectrometry (ICP-MS).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!