Background: Left atrial (LA) plication is a procedure used to correct an LA that expands posteriorly due to remodeling. This study aimed to determine the efficacy of additional LA plication in reducing postoperative cardiovascular events (CVEs) after mitral valve (MV) repair in atrial functional mitral regurgitation (MR) patients.
Methods: Between October 2008 and August 2023, MV repair with or without LA plication in 74 patients was studied. This study examined the efficacy of concomitant LA plication during MV repair.
Results: All patients underwent mitral annuloplasty. Of these, 26 underwent additional LA plication. In the mid-term periods, protruding posterior LA length in patients with LA plication was shorter than those without LA plication (2.8±0.49 . 3.3±0.72 cm, P=0.01). The percentage change in aortomitral angle from preoperative to mid-term periods in patients with LA plication was bigger than those without LA plication (1.04°±0.102° . 0.98°±0.084°, P=0.01). Posterior leaflet coaptation angle in patients with LA plication was smaller than those without LA plication (42°±15° . 76°±30°, P<0.001). A postoperative posterior leaflet coaptation angle of 101° had the maximum sum of sensitivity and specificity in predicting postoperative CVEs (96.9% and 76.9%, respectively). Patients with a postoperative posterior leaflet coaptation angle of 101° or higher had a poorer prognosis than those with an angle less than 101°, with an event-free rate of 18% . 80% at 7 years after surgery (P<0.0001).
Conclusions: Additional LA plication might be useful in reducing postoperative CVEs in atrial functional MR patients.
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http://dx.doi.org/10.21037/jtd-24-593 | DOI Listing |
Front Endocrinol (Lausanne)
December 2024
Department of Gastroenterology, The First Hospital of Jilin University, Changchun, China.
In contemporary microbial research, the exploration of interactions between microorganisms and multicellular hosts constitutes a burgeoning field. The gut microbiota is increasingly acknowledged as a pivotal contributor to various disorders within the endocrine system, encompassing conditions such as diabetes and thyroid diseases. A surge in research activities has been witnessed in recent years, elucidating the intricate interplay between the gut microbiota and disorders of the endocrine system.
View Article and Find Full Text PDFCureus
November 2024
Department of Cardiothoracic Surgery, Castle Hill Hospital, Cottingham, GBR.
This case report describes a rare instance of massive right ventricular myxoma (RVM). A 36-year-old woman initially presented with progressive breathlessness and chest heaviness. Imaging revealed a large mass in the mediastinum, which was initially thought to be a pericardial cyst, and it was unclear whether the mass was intracardiac or extracardiac.
View Article and Find Full Text PDFArch Gynecol Obstet
December 2024
Department of Gynecology, First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Dong Road, ErQi District, Zhengzhou, 450001, China.
Background: Stress urinary incontinence (SUI) is prevalent among women, often occurring alongside anterior vaginal wall prolapse. This study compares the efficacy and safety of an improved vaginal wall repair technique with pubocervical fascia fixation versus standard anterior colporrhaphy for treating SUI in women with anterior vaginal wall prolapse.
Methods: A single-centre, parallel-group, randomised controlled trial was conducted between September 2021 and June 2024.
Asian J Androl
December 2024
Department of Maternal Infant and Urologic Sciences, "Sapienza" University of Rome, Policlinico Umberto I Hospital, Rome 00161, Italy.
Implantation of inflatable penile prosthesis should be considered as a definitive treatment of erectile dysfunction. However, the sole procedure might not allow for optimal dimensional and functional outcomes. The aim of this study was to systematically review the literature and present the findings on the optimal choice of perioperative methods, surgical techniques, and pharmacotherapy to improve penile length, curvature, and erectile function.
View Article and Find Full Text PDFJ Sex Med
December 2024
Department of Urology, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, United States.
Background: Inflatable penile prosthesis (IPP) insertion is recommended for the treatment of patients with Peyronie's disease (PD) and significant erectile dysfunction (ED); adjunctive procedures can be used for residual curvature after IPP placement.
Aim: To assess the management of penile curvature correction in PD patients undergoing IPP procedures within a large multinational, multicenter cohort.
Methods: A retrospective analysis was conducted on PD patients treated with IPP by 11 experienced prosthetic surgeons.
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