Exercise prehabilitation may improve the tolerance and effectiveness of anticancer treatments such as chemotherapy. This systematic review assesses the impact of exercise on chemotherapy outcomes and identifies research priorities. Nineteen studies (1418 patients) were reviewed, including 11 randomised controlled trials and eight observational studies. Exercise led to improvements in body composition, fitness, strength and quality of life (QoL) across studies. Exercise can be safely and effectively delivered during chemotherapy. Limited standardisation and small sample sizes highlight the need for larger, better-designed studies to optimise this low-cost intervention.
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http://dx.doi.org/10.1002/jso.27845 | DOI Listing |
J Forensic Odontostomatol
December 2024
Department of Medicine and Health Science "Vincenzo Tiberio", University of Molise, AgeEstimation Project, Campobasso, Italy.
Forensic age estimation is performed by assessing pulp chamber constrictions due to physiological age-related changes in dental radiographs; however, the estimated ages occasionally deviate from the actual ages. In particular, long-term steroid users tend to demonstrate pulp chamber constrictions in all teeth. Because this is uncommon among younger age groups, caution should be exercised when evaluating pulp chamber constriction.
View Article and Find Full Text PDFSynapse
January 2025
Center for Neural Science, New York University, New York, New York, USA.
Objective: Anorexia nervosa (AN) is an eating disorder with the second highest mortality of all mental illnesses and high relapse rate, especially among adult females, yet with no accepted pharmacotherapy. A small number of studies have reported that adult females who struggled with severe and relapsing AN experienced sustained remission of the illness following ketamine infusions. Two other reports showed that 30 mg/kg IP ketamine can reduce vulnerability of adolescent mice to activity-based anorexia (ABA), an animal model of AN.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Universidade do Vale do Rio dos Sinos, São Leopoldo, Rio Grande do Sul, Brazil.
Background: In recent years, researchers have linked epigenetic factors to numerous diseases, one of them being Alzheimer's Disease (AD). Those factors may lead to the disease but also serve as a path for new treatments and prevention methods.
Method: A wide selection of articles in the PubMed platform that focused on epigenetics, Alzheimer's Disease, and correlating aspects among them were reviewed.
Nirmatrelvir/ritonavir is a novel drug combination authorized by the US Food and Drug Administration for the treatment of coronavirus disease 2019 (COVID-19). This report describes the case of a patient with a prior history of kidney transplantation who received nirmatrelvir/ritonavir. In this case, sirolimus use was successfully stopped before nirmatrelvir/ritonavir treatment, and the nirmatrelvir/ritonavir trough concentration was determined.
View Article and Find Full Text PDFBMC Nephrol
January 2025
Department of Nephrology, Huadu District People's Hospital of Guangzhou, Guangzhou, 510800, China.
Purpose: To investigate the current status of medication adherence among peritoneal dialysis (PD) patients in a primary hospital and to explore the influencing factors of medication adherence among PD patients.
Methods: The author used the Chinese version of the Morisky Medication Compliance Scale to evaluate the medication compliance of 226 PD patients in a single centre. Univariate analysis and logistic regression were used to analyse the factors influencing medication compliance in patients.
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