Although single women and lesbian couples are given access to donor spermatozoa, all kinds of restrictions limit their actual use of donor insemination. These restrictions are frequently justified by the increase in safety (lowering the genetic risk) or well-being of donor-conceived persons. However, these restrictions directly result in stratified reproduction in which only the rich (those with the necessary financial means) and the straight (those who conform to dominant views of parenthood) are allowed to reproduce.
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http://dx.doi.org/10.1016/j.rbmo.2024.104434 | DOI Listing |
Gynecol Obstet Fertil Senol
December 2024
Endocrinologue-Diabétologue, chef de service d'Endocrinologie, Hôpital l'Archet, CHU Nice, 151 route de Saint Antoine de Ginestière, 06 200 NICE, France. Electronic address:
Objectives: The Bioethics Law of August 2nd, 2021 established access to origins for people conceived by gamete donation. Two years after the implementation of this disposition, what is the proportion of former gamete donors informed about access to origins, and what is their position on this matter? What could be the potential repercussions of this new law on them? .
Methods: Retrospective single-center cohort study using questionnaires Results: When former gamete donors were asked about access to origins, only 53 % of oocytes donors and 71 % of sperm donors were aware of this measure.
Immunohematology
December 2024
Transfusion Medicine, Dr. Rela Institute & Medical Centre, Bharath Institute of Higher Education and Research, Chennai, Tamilnadu, India.
Red blood cell (RBC) alloimmunization can occur because of exposure to various sensitizing factors and poses a constant threat in transfusion. Assisted reproductive technology (ART) involves manipulation of sperm, ova, or embryos with the goal of producing a pregnancy. We present an interesting case of ART-induced maternal alloimmunization (AIMA) due to anti-c in a woman carrying a twin pregnancy.
View Article and Find Full Text PDFRedox Biol
December 2024
State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproduction and Genetics, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, 215002, China. Electronic address:
Male infertility, frequently driven by oxidative stress, impacts half of infertile couples globally. Despite its significance, the precise mechanisms governing this process remain elusive. In this study, we demonstrate that ASB1, the substrate recognition subunit of a ubiquitin ligase, is highly expressed in the mouse testis.
View Article and Find Full Text PDFSci Rep
December 2024
Complete Fertility, Princess Anne Hospital, Level F, Coxford Road, Southampton, SO16 5YA, UK.
Elevated progesterone (EP) or inadequate progesterone levels during ART cycle monitoring may lead to cycle cancellations or further progesterone supplementation, but practice varies. It remains controversial whether modifying clinical practice in the presence or absence of EP improves clinical outcomes. This systematic review aims to investigate if progesterone levels at different phases of fresh and frozen ART cycles influence pregnancy outcomes, in particular, that pertaining to day 3 versus day 5 embryo transfers.
View Article and Find Full Text PDFFront Reprod Health
December 2024
Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, OH, United States.
Research Question: Male infertility accounts for almost half of all infertility cases worldwide, with idiopathic male infertility accounting for up to 30% of the cases. Sperm proteomics has revealed critical molecular pathway changes in men with infertility. However, the sperm mitochondrial proteome remains poorly understood.
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