Rationale And Objectives: Accurate assessment of fetal head station (FHS) is crucial during labor management to reduce the risk of complications and plan the mode of delivery. Although digital vaginal examination (DVE) has been associated with inaccuracies in FHS assessment, ultrasound (US) evaluation remains dependent on sonographer expertise. This study aimed at investigating the reliability and accuracy of an automatic approach to assess the FHS during labor with transperineal US (TPU).
Materials And Methods: In this prospective observational study, 27 pregnant women in the second stage of labor, with fetuses in cephalic presentation, underwent conventional labor management with additional TPU examination. A total of 45 2D B-mode TPU acquisitions were performed at different FHS, before performing DVE. The FHS was assessed by the algorithm (FHS) on TPU images and by DVE (FHS). The sonographic assessment of FHS by expert sonographer (FHS) on the same TPU acquisition used for the automatic measurement served as gold standard. The performance and accuracy were assessed through Spearman's ρ, the coefficient of determination (R), root mean square error (RMSE), and Bland-Altman analysis.
Results: A strong correlation between FHS and FHS (ρ = 0.97, p < 0.001) and a high coefficient of determination (R = 0.95) were found. A lower correlation with FHS (ρ = 0.66, p < 0.001) and coefficient of determination (R = 0.52) was found for DVE. Moreover, the RMSE reported higher accuracy of FHS (RMSE = 0.32 cm) compared to FHS (RMSE = 0.97 cm). Bland-Altman analysis showed that the algorithm performed with smaller bias and narrower limits of agreement compared to DVE.
Conclusion: The proposed algorithm can evaluate FHS with high accuracy and low RMSE. This approach could facilitate the use of US in labor, supporting the clinical staff in labor management.
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http://dx.doi.org/10.1016/j.ultrasmedbio.2024.09.022 | DOI Listing |
Adv Sci (Weinh)
January 2025
Faculty of Health Sciences, University of Macau, Macau SAR, 999078, China.
Imaging abnormal copper/iron with effective fluorescent tools is essential to comprehensively put insight into many pathological events. However, conventional coordination-based detection is mired in the fluorescence quenching induced by paramagnetic Cu(II)/Fe(III). Moreover, the strong chelating property of the probe will consume dissociative metal ions and inevitably interfere with the physiological microenvironment.
View Article and Find Full Text PDFBMC Public Health
January 2025
Department of Public Health, Faculty of Health Sciences, University of Venda, University Rd, Thohoyandou, South Africa.
Background: The reasons for men not to seek healthcare seem similar across the world. They avoid going for regular medical check-ups, and preventive care and often disregard symptoms or delay seeking medical attention when sick, in pain, or even when their lives are in danger.
Methods: This study sought to explore the views of men on factors contributing to poor health-seeking behavior among men in Mopani, Vhembe, and Capricorn district municipalities in Limpopo Province.
BMC Public Health
January 2025
Department of Public Health, Faculty of Health Sciences, University of Venda, 1 University Road, Thohoyandou, 0950, South Africa.
Introduction: The orphan and vulnerable children crisis has raised the need for alternative solutions to their problems. These new alternatives gave prominence to the growth of community-based organisations and their interventions. Community-based interventions are a crucial component of the response to ensure that the demands of orphans and vulnerable children are mitigated as they offer initial support and act as well-being nets.
View Article and Find Full Text PDFExp Mol Med
January 2025
Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.
FHIT is a fragile site tumor suppressor that is primarily inactivated upon tobacco smoking. FHIT loss is frequently observed in lung cancer, making it an important biomarker for the development of targeted therapy for lung cancer. Here, we report that inhibitors of glycogen synthase kinase 3 beta (GSK3β) and the homologous recombination DNA repair (HRR) pathway are synthetic lethal with FHIT loss in lung cancer.
View Article and Find Full Text PDFClin Park Relat Disord
December 2024
Boston University, School of Public Health, Boston, MA, USA.
Objective: To determine the role of obesity in the development of Parkinson's disease (PD).
Background: Obesity has been reported to be both a risk factor for PD, as well as potentially protective. The Framingham Heart Study (FHS) is a multigenerational longitudinal cohort study that was started in 1948, which is well-known for its cardiovascular health studies.
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