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Exploring Virtual Reality and Exercise Simulator Interventions in Patients With Attention Deficit Hyperactivity Disorder: Comprehensive Literature Review.
JMIR Serious Games
January 2025
School of Computing, Engineering and Mathematical Sciences, Optus Chair Digital Health, La Trobe University, Melbourne, Australia.
Background: This review explores virtual reality (VR) and exercise simulator-based interventions for individuals with attention-deficit/hyperactivity disorder (ADHD). Past research indicates that both VR and simulator-based interventions enhance cognitive functions, such as executive function and memory, though their impacts on attention vary.
Objective: This study aimed to contribute to the ongoing scientific discourse on integrating technology-driven interventions into the management and evaluation of ADHD.
Deep Thermalization in Gaussian Continuous-Variable Quantum Systems.
Phys Rev Lett
December 2024
National University of Singapore, Department of Physics, Singapore 117551.
We uncover emergent universality arising in the equilibration dynamics of multimode continuous-variable systems. Specifically, we study the ensemble of pure states supported on a small subsystem of a few modes, generated by Gaussian measurements on the remaining modes of a globally pure bosonic Gaussian state. We find that beginning from highly entangled, complex global states, such as random Gaussian states and product squeezed states coupled via a deep array of linear optical elements, the induced ensemble attains a universal form, independent of the choice of measurement basis: it is composed of unsqueezed coherent states whose displacements are distributed normally and isotropically, with variance depending on only the particle-number density of the system.
View Article and Find Full Text PDFA mitochondria-targeted iridium(III) complex-based sensor for endogenous GSH detection in living cells.
Analyst
January 2025
Jiangxi Provincial Key Laboratory of Organic Functional Molecules; Institute of Organic Chemistry, Jiangxi Science and Technology Normal University, Nanchang 330013, PR China.
Glutathione (GSH) plays an important role in maintaining redox homeostasis in biological systems. Development of reliable glutathione sensors is of great significance to better understand the role of biomolecules in living cells and organisms. Based on the advantages of the photophysical properties of iridium complexes, we proposed a "turn-on" phosphorescent sensor.
View Article and Find Full Text PDFIdentification of Functionally-Relevant Lentivirus Integration Sites in an Insertional Mutagenesis Cell Library.
J Vis Exp
January 2025
State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University;
The extent of functional sequences within the human genome is a pivotal yet debated topic in biology. Although high-throughput reverse genetic screens have made strides in exploring this, they often limit their scope to known genomic elements and may introduce non-specific effects. This underscores the urgent need for novel functional genomics tools that enable a deeper, unbiased understanding of genome functionality.
View Article and Find Full Text PDFOrientation selectivity properties for the affine Gaussian derivative and the affine Gabor models for visual receptive fields.
J Comput Neurosci
January 2025
Computational Brain Science Lab, Division of Computational Science and Technology, KTH Royal Institute of Technology, SE-100 44, Stockholm, Sweden.
This paper presents an in-depth theoretical analysis of the orientation selectivity properties of simple cells and complex cells, that can be well modelled by the generalized Gaussian derivative model for visual receptive fields, with the purely spatial component of the receptive fields determined by oriented affine Gaussian derivatives for different orders of spatial differentiation. A detailed mathematical analysis is presented for the three different cases of either: (i) purely spatial receptive fields, (ii) space-time separable spatio-temporal receptive fields and (iii) velocity-adapted spatio-temporal receptive fields. Closed-form theoretical expressions for the orientation selectivity curves for idealized models of simple and complex cells are derived for all these main cases, and it is shown that the orientation selectivity of the receptive fields becomes more narrow, as a scale parameter ratio , defined as the ratio between the scale parameters in the directions perpendicular to vs.
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