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Factors Affecting Outcomes of Percutaneous Transluminal Angioplasty for Central Vein Occlusive Disease in the University of the Philippines-Philippine General Hospital: A 10-Year Experience.
Acta Med Philipp
November 2024
Division of Thoracic, Cardiac and Vascular Surgery, Department of Surgery, College of Medicine and Philippine General Hospital, University of the Philippines Manila.
Objective: To describe the treatment outcomes of patients who underwent Percutaneous Transluminal Angioplasty (PTA) for Central Vein Occlusive Disease (CVOD) in end-stage kidney disease and determine the association between patient profile and treatment outcomes.
Methods: A single-institution, retrospective review of patients aged 18 and above with end-stage kidney disease who underwent PTA for CVOD in the University of the Philippines - Philippine General Hospital (UP-PGH) from January 1, 2013, to December 31, 2022, was performed. These patients' demographic and clinical profiles were evaluated using means, frequencies, and percentages.
Early neutrophil activation and NETs release in the pristane-induced lupus mice model.
PLoS One
January 2025
Laboratório de Imunologia Celular (LIM-17), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Article Synopsis
- The study investigates the role of NETosis in the initiation of lupus using a mouse model.
- Mice injected with pristane showed significantly more activated neutrophils and low-density granulocytes, as well as increased release of neutrophil extracellular traps compared to the control group.
- These findings suggest that early activation of neutrophils and NETosis may contribute to the development of lupus in this model.
Risk factors for venous thromboembolism in patients with chronic kidney disease: a systematic review and meta-analysis.
Ren Fail
December 2024
School of Medicine, Renal Department and Nephrology Institute, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Purpose: The objective of this study was to conduct a meta-analysis and systematic review to identify the risk factors contributing to thromboembolism (VTE) in chronic kidney disease (CKD) patients.
Methods: PubMed, Cochrane Library, Web of Science, and Embase databases were searched from inception to October 2024. Cohort, case-control, and cross-sectional studies examining risk factors for VTE in CKD were included.
Trained Mesenchymal Stromal Cell-Based Therapy HXB-319 for Treating Diffuse Alveolar Hemorrhage in a Pristane-induced Murine Model.
Stem Cells
November 2024
Department of Pathology, School of Medicine, Case Western Reserve University, Cleveland, Ohio.
Introduction: Mesenchymal stromal cells (MSCs) can modulate immune responses and suppress inflammation in autoimmune diseases. Although their safety has been established in clinical trials, the efficacy of MSCs is inconsistent due to variability in potency among different preparations and limited specificity in targeting mechanisms driving autoimmune diseases.
Methods: We utilized High-Dimensional Design of Experiments methodology to identify factor combinations that modulate gene expression by MSCs to mitigate inflammation.
Pericardial Hernia After Pericardial Window: A Rare Case.
Cureus
September 2024
General Surgery, Manchester University NHS Foundation Trust, Manchester, GBR.
Article Synopsis
- Diaphragmatic hernias, traditionally linked to birth defects or trauma, can also occur due to surgical procedures, as shown in a rare case involving a 59-year-old woman after pericardial window surgery.
- The patient experienced shortness of breath post-surgery, and imaging revealed an intrapericardial diaphragmatic hernia, leading to an open surgery for repair.
- This case underscores the importance of recognizing and addressing rare complications like these postoperatively, highlighting the need for careful planning and intervention to prevent serious cardiac issues.
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