Polysaccharides could be used to form the network structure of casein (CA) gel, and affect its gelling properties. Auricularia auricula polysaccharide (AAP) has good gel properties and activity, however, how the AAP affects gelling properties of CA gels remains unclear. In this study, AAP and CA were acid-induced by glucono-δ-lactone (GDL) to prepare composite gels for curcumin loading. The effects of different AAP additions on the gel structure were emphasized. Water holding capacity, rheology, texture profile analysis, sulfhydryl content, surface hydrophobicity and gel microstructure showed that the composite gels were most structurally stable upon addition of 0.4 % AAP. The composite gels exhibited a higher strength and a more regular network structure compared to the CA gels. The results of turbidity studies showed that CA and AAP formed gels through electrostatic interactions due to pH < pI. The results of FT-IR, X-ray diffraction, fluorescence spectroscopy, and UV-Vis spectroscopy indicated that curcumin interacted with the CA and was successfully encapsulated within the gel. In addition, in vitro simulated digestion experiments demonstrated that the composite gels exhibited better protection against curcumin than the single CA gel. The results suggested that composite gels can be used as a curcumin carrier, which may enhance its wider application in the food and health industries.
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http://dx.doi.org/10.1016/j.ijbiomac.2024.136777 | DOI Listing |
Antioxidants (Basel)
January 2025
State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China.
Whey protein isolate (WPI) has functional properties such as gelation and emulsification. Emulsion gels combine the benefits of both emulsions and hydrogels. In this study, WPI hydrogels and emulsion gels were developed with goji oil (GO) as the oil phase by the inclusion of blueberry extract (BE) in the protein matrix.
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January 2025
Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, I-44121, Ferrara, Italy.
In this study an in situ forming gel for curcumin and piperine delivery is investigated as a long-lasting strategy in the local treatment of inflammatory and degenerative joint disease, such as osteoarthritis and rheumatoid arthritis. Particularly glyceryl monooleate, in association with phosphatidylcholine and ethanol, were employed. Different ratios between excipients were tested, with the aim to obtain a liquid form suitable for subcutaneous injection, gaining a semisolid consistency in contact with biological fluids.
View Article and Find Full Text PDFGels
January 2025
Institute for Polymers and Composites, University of Minho, 5800-048 Guimarães, Portugal.
A set of carrageenans produced in the potassium form and with chemical structures varying from pure iota-carrageenans to nearly pure kappa-carrageenans is submitted to ultrasonication to reduce their molecular masses Mw while maintaining a constant chemical structure and a polydispersity index around 2. The kinetics of ultrasound-induced chain scission are found to be slower for polysaccharides richer in kappa-carrageenan disaccharide units. From the elasticity of samples directly gelled in a rheometer at 1 /% in 0.
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January 2025
Department of Biomedical Sciences and Engineering, National Central University, Taoyuan City 320317, Taiwan.
Skin cancer is the world's fifth most diagnosed malignancy and is increasingly occurring in young adults. The elevated morbidity and mortality of skin cancer are known to be highly correlated with its frequent recurrence after tumor excision. Although regimens such as chemotherapy and/or immunotherapy are often administered following surgical treatments, the patients may suffer from severe side effects, drug resistance, and/or high cost during treatments, indicating that the development of an effective and safe modality for skin cancer after surgery is still highly demanded nowadays.
View Article and Find Full Text PDFGels
January 2025
School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.
The escalating global climate crisis and energy challenges have made the development of efficient radiative cooling materials increasingly urgent. This study presents a machine-learning-based model for predicting the performance of radiative cooling aerogels (RCAs). The model integrated multiple parameters, including the material composition (matrix material type and proportions), modification design (modifier type and content), optical properties (solar reflectance and infrared emissivity), and environmental factors (solar irradiance and ambient temperature) to achieve accurate cooling performance predictions.
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