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Blood lipid metabolic biomarkers are emerging as significant prognostic indicators for survival in cancer patients.
BMC Cancer
December 2024
Department of Radiotherapy and Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Background: Dyslipidemia is a common comorbidity in patients with cancer, yet the impact of abnormal lipid levels on tumor prognosis remains contentious. This study was conducted to synthesize the current evidence regarding the prognostic utility of blood lipid levels, including high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), triglycerides (TG), apolipoprotein A1 (ApoA1), and apolipoprotein B (ApoB), in predicting overall survival (OS) and disease-free survival (DFS) in cancer patients.
Methods: A comprehensive literature search was performed across electronic databases to assess the associations between blood lipid levels and OS or DFS in cancer patients.
Efficacy of Jiangzhi Mai'an Granules in the treatment of stable angina pectoris with phlegm and blood stasis obstruction and carotid artery plaque: A prospective randomized study.
Medicine (Baltimore)
December 2024
Department of Cardiology, Kunshan Hospital of Traditional Chinese Medicine, Suzhou, Jiangsu, China.
Background: Stable angina pectoris, resulting from coronary artery atherosclerosis, significantly affects quality of life and carries a high risk of cardiovascular events. Despite modern therapies, managing this condition remains challenging. Traditional Chinese medicine (TCM) views it as a syndrome of heart meridian obstruction by phlegm and blood stasis, necessitating improved circulation and phlegm resolution.
View Article and Find Full Text PDFApolipoprotein B/Apolipoprotein A1 ratio is an independent prognostic factor in pancreatic cancer.
Transl Oncol
January 2025
Department of Cardiology, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, PR China. Electronic address:
Article Synopsis
- The study aimed to explore how serum lipid levels relate to the prognosis of pancreatic cancer in patients.
- Researchers analyzed data from 286 patients over four years and assessed factors like clinical characteristics and survival rates.
- They found that high levels of apolipoprotein B/apolipoprotein A1 (ApoB/ApoA1) are linked to shorter overall and progression-free survival, suggesting it could be an important prognostic factor for pancreatic cancer.
Blood lipid profiles associated with metastatic sites in advanced gastric cancer.
BMC Gastroenterol
November 2024
Department of Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Article Synopsis
- This study investigates the relationship between blood lipid levels and disease characteristics in patients with advanced gastric cancer, specifically focusing on how these lipid levels change as the disease progresses.
- Researchers analyzed data from 179 patients with stage III-IV gastric adenocarcinoma, looking at various lipid parameters and their association with factors like age, gender, and metastasis sites.
- The findings suggest that certain lipid levels, such as low total cholesterol and specific changes in LDL-C and VLDL-C, are linked to different metastatic sites, indicating that lipid profiles could be useful biomarkers for predicting where the cancer spreads in patients.
ApoB and prognosis of patients with chronic coronary syndrome.
Rev Esp Cardiol (Engl Ed)
October 2024
Servicio de Cardiología, Hospital Universitario de Jaén, Jaén, Spain.
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