Healthcare systems in Canada are under pressure and require change-the status quo is no longer fit for purpose, if it ever was. Innovation is often held up as a cure for what ails us, but shiny new things or novel technologies alone have not been enough. This article will explore the concepts of differentiation and integration as being important drivers in the evolution of living organisms, ecosystems, and complex human organizations. The implications of this deep pattern of systems change are essential to understanding the roles of specialization in medicine, and optionality in primary care. Specifically, overspecialization without attention to the principles of healthcare integration can lead to fragmentation of care and worse patient outcomes. Finally, this article will describe some practical examples of system integration as innovation in the form of better public health and care delivery connections, health homes, and community care coordination centres.
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http://dx.doi.org/10.1177/08404704241292629 | DOI Listing |
Nurse Educ
January 2025
Authors Affiliations: Department of Biobehavioral Nursing Science (Drs Castro, Stephens, and Vanderzwan), Department of Human Development Nursing Science (Ms Ortiz), College of Nursing, University of Illinois at Chicago, Chicago, IL.
Background: Nursing students are not consistently trained on how to care for patients experiencing sudden cardiac arrest. In rapid cycle deliberate practice (RCDP), learners perform a simulation with micro-debriefs interjected by the instructor.
Problem: RCDP has been used to train health care students on how to respond during a sudden cardiac arrest, but its application to prelicensure nursing students is underreported.
Nurse Educ
January 2025
Author Affiliations: Arizona State University Edson College of Nursing and Health Innovation, Phoenix, Arizona (Dr Heywood); Wichita State University School of Nursing, Wichita, Kansas (Dr Williams); Southern New Hampshire University Nursing and Health Professions Department, Manchester, New Hampshire (Dr Blackwell); Bemidji State University Department of Nursing, Bemidji, Minnesota (Dr Hommes); University of Mississippi Medical Center School of Nursing, Jackson, Mississippi (Professor Franklin); and Boise State University School of Nursing, Boise, Idaho (Dr Nichols).
Background: The recent American Association of Colleges of Nursing (AACN) Essentials revision emphasizes direct clinical experiences across 4 spheres of care in RN-Baccalaureate (RN-B) education, creating challenges for online, asynchronous programs. Differentiating between prelicensure and postlicensure education complicates the integration of these requirements. Understanding RN-B faculty needs is critical for curricular transformation.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Surgical and Medical Sciences, Magna Graecia University of Catanzaro, Catanzaro, Italy.
Plant viruses pose a significant threat to global agriculture and require efficient tools for their timely detection. We present AutoPVPrimer, an innovative pipeline that integrates artificial intelligence (AI) and machine learning to accelerate the development of plant virus primers. The pipeline uses Biopython to automatically retrieve different genomic sequences from the NCBI database to increase the robustness of the subsequent primer design.
View Article and Find Full Text PDFJCI Insight
January 2025
Medical Oncology Department, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, Netherlands.
Background: Previously, we demonstrated that changes in circulating tumor DNA (ctDNA) are promising biomarkers for early response prediction (ERP) to immune checkpoint inhibitors (ICI) in metastatic urothelial cancer (mUC). In this study, we investigated the value of whole blood immunotranscriptomics for ERP-ICI and integrated both biomarkers into a multimodal model to boost accuracy.
Methods: Blood samples of 93 patients were collected at baseline and after 2-6 weeks of ICI for ctDNA (N=88) and immunotranscriptome (N=79) analyses.
JMIR Public Health Surveill
January 2025
Monitoring, Evaluation, and Learning Platform USAID, Jakarta, Indonesia.
Background: Indonesia's vast archipelago and substantial population size present unique challenges in addressing its multifaceted HIV epidemic, with 90% of its 514 districts and cities reporting cases. Identifying key populations (KPs) is essential for effectively targeting interventions and allocating resources to address the changing dynamics of the epidemic.
Objective: We examine the 2022 mapping of Indonesia's KPs to develop improved HIV and AIDS interventions.
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