AI Article Synopsis

  • Invasive fungal infections are common in hospitals and lead to significant health risks, affecting many patients with high rates of morbidity and mortality.
  • The study aimed to identify the top 10 most influential articles from 2018 to 2023 regarding the treatment of these infections using a three-step consensus approach with expert panels.
  • The final list of recommended publications focuses on treating conditions like invasive aspergillosis, candidiasis, and cryptococcosis, serving as a valuable resource for clinicians to enhance their antifungal treatment strategies.

Article Abstract

Background: Invasive fungal infections are responsible for a large number of infections in hospitalized patients annually and are responsible for high morbidity and mortality. Familiarity with novel agents or strategies in this area can be challenging.

Objectives: To identify the top 10 manuscripts on the treatment of invasive fungal infections from 2018 to 2023.

Design: Modified Delphi consensus-building technique.

Methods: A three-stage consensus-building approach was used comprised of (1) identifying relevant articles; (2) voting by a panel of experts to establish consensus on the importance of these articles; and (3) finalizing the list of top articles by a small group. Members of the Southeastern Research Group Endeavor network served as content experts. Publications from 2018 to 2023 were evaluated if articles met the following inclusion criteria: (1) published between 2018 and 2023, (2) contained content related to fungal infections, and (3) included an actionable intervention.

Results: A total of 6518 potential publications were assessed. After applying inclusion and exclusion criteria, 82 articles were reviewed. The top 10 publications related to invasive fungal infections, selected by a panel of experts, are summarized in this manuscript and include publications related to the treatment of invasive aspergillosis, candidiasis, and cryptococcosis.

Conclusion: This article highlights the selected publications and may serve as a key resource for teaching and training. Clinicians may also employ these reported interventions to identify new opportunities to optimize antifungal therapeutic strategies within one's institution.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11494669PMC
http://dx.doi.org/10.1177/20499361241290349DOI Listing

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