The conundrum of the giant condyloma: is it carcinoma?

J Surg Case Rep

Department of General Surgery, Virginia Mason Franciscan Health, 1100 9th Ave, Seattle, WA 98101, United States.

Published: October 2024

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Article Abstract

Perineal verrucous carcinoma is a rare variant of squamous cell carcinoma that is mainly treated with surgical excision. In this case report, we present a 58-year-old man with human immunodeficiency virus who presented with an extraordinarily large perineal mass that was ultimately found to be verrucous carcinoma in association with giant condyloma acuminata. He was treated with a wide local excision followed by staged abdominoperineal resection and fasciocutaneous flap reconstruction. In the post-operative course, the patient developed relatively short interval recurrence which was successfully managed with salvage radiotherapy. He is now post-radiation without evidence of recurrence.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495325PMC
http://dx.doi.org/10.1093/jscr/rjae668DOI Listing

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The giant condyloma acuminatum, known as the Buschke-Löwenstein tumor (BLT), is an uncommon, slow-growing, cauliflower-like tumor located in the anogenital region. It has a high recurrence rate, is sexually transmitted, and is often linked with immunosuppression. This tumor is commonly associated with human papillomavirus (HPV) infection, making HPV one of the most prevalent sexually transmitted infections affecting the perineal and genital regions.

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The conundrum of the giant condyloma: is it carcinoma?

J Surg Case Rep

October 2024

Department of General Surgery, Virginia Mason Franciscan Health, 1100 9th Ave, Seattle, WA 98101, United States.

Article Synopsis
View Article and Find Full Text PDF

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