Perineal verrucous carcinoma is a rare variant of squamous cell carcinoma that is mainly treated with surgical excision. In this case report, we present a 58-year-old man with human immunodeficiency virus who presented with an extraordinarily large perineal mass that was ultimately found to be verrucous carcinoma in association with giant condyloma acuminata. He was treated with a wide local excision followed by staged abdominoperineal resection and fasciocutaneous flap reconstruction. In the post-operative course, the patient developed relatively short interval recurrence which was successfully managed with salvage radiotherapy. He is now post-radiation without evidence of recurrence.
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http://dx.doi.org/10.1093/jscr/rjae668 | DOI Listing |
Cureus
November 2024
Emergency Medicine, Public Health Institution Dom Zdravlja Prijedo, Prijedor, BIH.
The giant condyloma acuminatum, known as the Buschke-Löwenstein tumor (BLT), is an uncommon, slow-growing, cauliflower-like tumor located in the anogenital region. It has a high recurrence rate, is sexually transmitted, and is often linked with immunosuppression. This tumor is commonly associated with human papillomavirus (HPV) infection, making HPV one of the most prevalent sexually transmitted infections affecting the perineal and genital regions.
View Article and Find Full Text PDFJ Surg Case Rep
October 2024
Department of General Surgery, Virginia Mason Franciscan Health, 1100 9th Ave, Seattle, WA 98101, United States.
Front Oncol
August 2024
Department of Thyroid and Breast Surgery, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
GCA, also known as Buschke-Lowenstein tumor, is a rare sexually transmitted disease associated with HPV types 6 and 111. These warts are considered histologically benign, but there is a risk of localized invasion and development of malignancy. This malignant transformation occurs most often in the perianal and vulvar areas, and involvement of other sites is relatively rare2.
View Article and Find Full Text PDFUrology
November 2024
Department of Surgery, Division of Urology, Federal University of São Paulo, São Paulo, São Paulo, Brazil.
J Pers Med
August 2024
Department 11, Discipline Plastic and Reconstructive Surgery, Bucharest Clinical Emergency Hospital, University of Medicine and Pharmacy Carol Davila, 050474 Bucharest, Romania.
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