AI Article Synopsis
- The COVID-19 pandemic led to a significant decrease in invasive meningococcal disease (IMD) cases due to health restrictions, but this also resulted in lower vaccination rates.
- After restrictions were lifted, IMD cases rebounded quickly, with a notable increase among adolescents and young adults, surpassing pre-pandemic levels by 2023.
- Changes in epidemiology and genotyping were observed, particularly for serogroups W and Y, while cases of serogroup C remained low due to effective childhood vaccination programs.
Article Abstract
RECENT EVOLUTION OF THE EPIDEMIOLOGY AND BURDEN OF INVASIVE MENINGOCOCAL DISEASE. The landscape of invasive meningococcal disease (IMD) has changed considerably since the COVID-19 pandemic. The number of cases has decreased significantly following the non-pharmaceutical interventions employed to counter the pandemic, but vaccination rates were also lower during the pandemic than pre-pandemic levels. Once the health restrictions were lifted, IMD rapidly rebounded, initially with a resurgence in adolescents/young adults, then in other age groups, reaching a higher number of cases in 2023 than in the pre-pandemic period, with profound epidemiological and genotypic changes, particularly for serogroups W and Y. The number of serogroup C cases remains very low, thanks to the protection offered by the serogroup C conjugate vaccination program for children.
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