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Application of Flow Cytometry Immunophenotypic Analysis for the Diagnosis of Mature B-Cell Lymphomas/Leukemias.
Hum Pathol
December 2024
Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Electronic address:
Flow cytometry immunophenotypic analysis is an important and indispensable tool in the diagnosis of mature B-cell lymphomas/leukemias, particularly for small fine needle aspiration and needle core biopsy specimens which are becoming increasingly popular for diagnostic purposes. Flow cytometry immunophenotyping (FCI) has several advantages. Given its multiparametric nature, FCI can analyze the expression of multiple antigens simultaneously on the same cell of interest, qualitatively and quantitively.
View Article and Find Full Text PDFA rare perspective: fine-needle aspiration cytologic features of hyaline vascular type of Castleman disease: A case report.
Medicine (Baltimore)
December 2024
Departments of Pathology, Qianjiang Central Hospital, Qianjiang, Hubei, China.
Rationale: Castleman disease, also known as Castleman syndrome, is a rare, nonmalignant lymphoproliferative disorder. The localized subtype of this disease is primarily the hyaline vascular type of Castleman disease (HVCD). Although this disease is a benign lesion, the histologic features are similar to those of some malignant lymphomas, so an accurate diagnosis of the disease is required.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the role of ultrasound-guided fine-needle aspiration biopsy (FNAB) in diagnosing thyroid nodules larger than 3 cm, emphasizing its significance for treatment decisions.* -
- Researchers reviewed patient records from 2018 to 2023, focusing on those who underwent thyroid surgery, categorizing them by nodule size to analyze FNAB outcomes.* -
- Results indicated that larger nodules (≥4 cm) had a higher rate of malignancy and more false negatives in FNAB, stressing the need for careful evaluation in surgical planning.*
A rapid turnaround time workflow for a cytological liquid biopsy assay using FNA supernatant specimens.
Cancer Cytopathol
January 2025
The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Background: Genomic profiling is essential in the management of non-small cell lung cancer. However, this may often be challenging because of limited cytological tissue and extended turnaround time (TAT) for next-generation sequencing (NGS). This study aims to describe a rapid TAT workflow for molecular profiling using fine-needle aspiration (FNA) supernatants.
View Article and Find Full Text PDFMass-forming type 2 autoimmune pancreatitis with upstream dilatation of the main pancreatic duct dilatation: a case report.
J Med Case Rep
December 2024
Department of Surgery 1, University of Fukui, 23-3 Matsuokashimoaizuki, Eiheiji-Cho, Yoshida-gun, Fukui, 910-1193, Japan.
Background: Type 2 autoimmune pancreatitis is characterized by multiple or segmental strictures of the main pancreatic duct without upstream dilatation. We encountered a case of mass-forming type 2 autoimmune pancreatitis with upstream main pancreatic duct dilatation that was difficult to diagnose preoperatively using endoscopic ultrasound sonography-guided fine-needle aspiration cytology.
Case Presentation: A 58-year-old Japanese man presented with recurrent acute pancreatitis secondary to a 10-mm pancreatic head tumor.
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