In this study, Phylloporia fontanesiae polysaccharide was successfully isolated through a sequential water extraction and alcohol precipitation process. Utilizing the Box-Behnken design, the extraction process was optimized based on single-factor experiments, considering variables such as the material-to-liquid ratio, extraction temperature, extraction time, and the number of extractions. The polysaccharide composition of P. fontanesiae is predominantly composed of mannose, glucuronic acid, glucose, and galactose, with a molar mass ratio of 4.31:4.10:36.83:1, along with minor amounts of aminoglucose and fucose. The polysaccharide fraction of P. fontanesiae comprises two distinct components, possessing relative molecular masses of 8.85 kDa and 134.03 kDa. Notably, the polysaccharide exhibited significant antioxidant activity. After undergoing simulated gastrointestinal digestion, no significant changes were observed in its antioxidant activity, molecular weight, or monosaccharide composition. This study not only enhanced the extraction efficiency of P. fontanesiae polysaccharide but also provided valuable insights into its composition, structure, and digestion characteristics. PRACTICAL APPLICATION: The optimum extraction process, stability, and antioxidant activity of Phylloporia fontanesiae polysaccharide during simulated digestion of gastrointestinal tract were studied. The results provide a theoretical basis for the development and application of this polysaccharide in the field of food and health products.
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http://dx.doi.org/10.1111/1750-3841.17381 | DOI Listing |
J Imaging Inform Med
January 2025
Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan.
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent chronic liver condition characterized by excessive hepatic fat accumulation. Early diagnosis is crucial as NAFLD can progress to more severe conditions like steatohepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma without timely intervention. While liver biopsy remains the gold standard for NAFLD assessment, abdominal ultrasound (US) imaging has emerged as a widely adopted non-invasive modality due to convenience and low cost.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
January 2025
Earth Sciences, Engineering Faculty, Autonomous University of San Luis Potosi, Av. Manuel Nava 8, San Luis Potosí, SLP, Mexico.
Ecosystems such as wetlands have karst groundwater as their primary source of preserving their services and functions. Karst systems are complex hydrogeological systems that are difficult to study because of their complicated functioning mechanism, which requires an interdisciplinary effort based on hydrodynamic assessment and characterization of the hydrogeology of the system. The study area is the Ramsar wetland Ciénaga de Tamasopo (Mexico), which is dependent on the discharge of karst groundwater that is affected by water extraction of extensive sugarcane agriculture and is also the main water source for the rural towns.
View Article and Find Full Text PDFNeuroinformatics
January 2025
Department of Information Technology, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Ramapuram, Chennai, 600089, India.
Brain tumours are one of the most deadly and noticeable types of cancer, affecting both children and adults. One of the major drawbacks in brain tumour identification is the late diagnosis and high cost of brain tumour-detecting devices. Most existing approaches use ML algorithms to address problems, but they have drawbacks such as low accuracy, high loss, and high computing cost.
View Article and Find Full Text PDFActa Otolaryngol
January 2025
Laboratory of Otoneurology British Hospital, Montevideo, Uruguay.
Background: Gait instability and falls significantly impact life quality and morbi-mortality in elderly populations. Early diagnosis of gait disorders is one of the most effective approaches to minimize severe injuries.
Objective: To find a gait instability pattern in older adults through an image representation of data collected by a single sensor.
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