Electrical stimulation mapping using depth stereo-EEG electrodes is an important method in the structure of presurgical diagnostics in patients with drug-resistant forms of epilepsy. Electrical stimulation mapping was first used in the 1960s and has been actively developed since then, but despite such a long history, a unified protocol for the use of this technique has not been developed and different approaches to stimulation mapping are used in different countries. Based on publications on the topic in PubMed and other available resources, we tried to briefly outline the current opinion on the significance of this technique, paying special attention to the methodological approaches of different schools to stimulation parameters when mapping epileptogenic zones, highlighting in a separate section approaches to stimulation of functionally significant zones Finally, we summarize data on the effectiveness of this method in the presurgical diagnostics of epilepsy.
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http://dx.doi.org/10.17116/jnevro20241240917 | DOI Listing |
Neuroinformatics
January 2025
Brainnetome Center, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China.
The position and orientation of transcranial magnetic stimulation (TMS) coil, which we collectively refer to as coil placement, significantly affect both the assessment and modulation of cortical excitability. TMS electric field (E-field) simulation can be used to identify optimal coil placement. However, the present E-field simulation required a laborious segmentation and meshing procedure to determine optimal coil placement.
View Article and Find Full Text PDFNeurorehabil Neural Repair
January 2025
Institute for Health and Sport (IHeS), Victoria University, Melbourne, VIC, Australia.
Non-invasive brain stimulation (NIBS) is sometimes used alongside medication to alleviate motor symptoms in people with Parkinson's disease (PD). However, the evidence supporting NIBS's effectiveness for improving motor function in PD patients is uncertain. .
View Article and Find Full Text PDFSci Transl Med
January 2025
Modular Implantable Neuroprostheses (MINE) Laboratory, Università Vita-Salute San Raffaele & Scuola Superiore Sant'Anna, 20132 Milan, Italy.
Spinal cord injury (SCI) causes severe motor and sensory deficits, and there are currently no approved treatments for recovery. Nearly 70% of patients with SCI experience pathological muscle cocontraction and spasticity, accompanied by clinical signs such as patellar hyperreflexia and ankle clonus. The integration of epidural electrical stimulation (EES) of the spinal cord with rehabilitation has substantial potential to improve recovery of motor functions; however, abnormal muscle cocontraction and spasticity may limit the benefit of these interventions and hinder the effectiveness of EES in promoting functional movements.
View Article and Find Full Text PDFCancers (Basel)
December 2024
Neurosurgery, Department of Neuroscience, Psychology, Pharmacology and Child Health, University Hospital of Careggi, University of Florence, 50134 Florence, Italy.
Navigated transcranial magnetic stimulation (nTMS) has seldom been used to study visuospatial (VS) circuits so far. Our work studied (I) VS functions in neurosurgical oncological patients by using repetitive nTMS (rnTMS), (II) the possible subcortical circuits underneath, and (III) the correspondence between nTMS and direct cortical stimulation (DCS) during awake procedures. We designed a monocentric prospective study, adopting a protocol to use rnTMS for preoperative planning, including VS functions for lesions potentially involving the VS network, including neurosurgical awake and asleep procedures.
View Article and Find Full Text PDFBiochem Mol Biol Educ
January 2025
College of Clinical Medicine, Hunan University of Chinese Medicine, Changsha, China.
The knowledge of "clinical molecular biology testing technology" is complex, conceptual expressions are abstract and difficult to understand, and the student's interest in learning is low. This study aimed to evaluate the effectiveness of a cyclic teaching method based on case analysis combined with an exploratory teaching method using mind mapping as an assignment. Students from the 2019 cohort of medical laboratory technology at Hunan University of Chinese Medicine served as the control group and received conventional lecture-based teaching methods.
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