AI Article Synopsis
- * Three pediatric cases illustrate various movement disorders, such as myoclonus, dystonia, and dyskinesias, highlighting the complexity of the symptoms associated with Powassan encephalitis.
- * These movement disorders significantly impact the patients' health, emphasizing the need for ongoing monitoring and flexible treatment options, and indicating that more research is needed to understand these conditions better.
Article Abstract
Background: The Powassan virus is a rare neurotropic, tick-borne arbovirus associated with meningoencephalitis. Despite the virus's known predilection for the basal ganglia, there are no reports detailing the spectrum of movement disorders in children with Powassan meningoencephalitis.
Cases: We present 3 cases of pediatric Powassan encephalitis, highlighting the diverse and evolving movement disorders associated with this disease. We observed subcortical myoclonus and progressive generalized dystonia (patient 1), transient dyskinesias and refractory focal dystonia (patient 2), and generalized dystonia evolving into chorea and lingual dyskinesias (patient 3). One patient exhibited multifocal vasculitis on magnetic resonance imaging angiography, a novel finding.
Conclusions: Movement disorders were a primary source of the morbidity experienced by pediatric Powassan encephalitis patients throughout their disease course, underscoring the importance of regular monitoring and adaptable treatment strategies in this condition. Larger, prospective studies are necessary to fully delineate the spectrum of associated movement disorders in this rare and severe disease.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11647971 | PMC |
| http://dx.doi.org/10.1002/mdc3.14245 | DOI Listing |
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