Environmental bacterial species is an emerging pathogen becoming increasingly important in causing human infections. Thus far, the clinical isolates of this species have not exhibited multidrug resistance very often, but some reports underline the necessity for continuous monitoring of this potentially dangerous pathogen. Currently, epidemiological surveillance and antimicrobial resistance investigations of any bacterial pathogen usually rely on whole genome sequencing, which is becoming more affordable while providing increasingly important data in the recent years. However, genomic information is scantily presented in public databases. Here, we report, to the best of our knowledge, the first whole genome sequence and corresponding raw data for a clinical isolate from Russian Federation, which carried antimicrobial resistance (AMR) genes, virulence factors, one plasmid, and CRISPR-Cas system of type I-F. The data provided will facilitate epidemiological surveillance and antimicrobial resistance monitoring of this emerging pathogen.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11492046PMC
http://dx.doi.org/10.1016/j.dib.2024.110973DOI Listing

Publication Analysis

Top Keywords

antimicrobial resistance
16
genome sequence
8
plasmid crispr-cas
8
crispr-cas system
8
emerging pathogen
8
epidemiological surveillance
8
surveillance antimicrobial
8
resistance
5
data
4
data analysis
4

Similar Publications

Novel inhibition of sortase A by plantamajoside: implications for controlling multidrug-resistant infections.

Appl Environ Microbiol

December 2024

Department of Gastrocolorectal Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, Jilin, China.

In confronting the significant challenge posed by multidrug-resistant (MDR) pathogens, particularly methicillin-resistant (MRSA), the development of innovative anti-infective strategies is essential. Our research focuses on sortase A (SrtA), a vital enzyme for anchoring surface proteins in . We discovered that plantamajoside (PMS), a phenylpropanoid glycoside extracted from .

View Article and Find Full Text PDF

Determination of antimicrobial resistance (AMR) in pneumococcal isolates is important for surveillance purposes and in a clinical context. Antimicrobial susceptibility testing (AST) of pneumococci is complicated by the need for exact minimal inhibitory concentrations (MICs) of beta-lactam antibiotics. Two next-generation sequencing (NGS) analysis tools have implemented the prediction of AMR in their analysis workflow, including the prediction of MICs: Pathogenwatch (https://pathogen.

View Article and Find Full Text PDF

Draft genome sequence of FH1.

Microbiol Resour Announc

December 2024

Agriculture Biotechnology Division, National Institute for Biotechnology and Genetic Engineering-College, Pakistan Institute of Engineering and Applied Sciences, Islamabad, Pakistan.

Phytopathogens with multi-drug resistance are emerging frequently, resulting in various disease outbreaks. Hence, exploring new antimicrobials is urgent. Here, we present the draft genome sequence of FH1 strain, with the potential to produce various antimicrobial compounds.

View Article and Find Full Text PDF

is an important bacterial pathogen implicated in infections such as mastitis, metritis, pneumonia, and liver abscesses in both domestic and wild animals, as well as endocarditis and prosthetic joint infections in humans. Understanding the genomic and metabolic features that enable to colonize different anatomical sites within a host and its inter-kingdom transmission and survival is important for the effective control of this pathogen. We employed whole-genome sequencing, phenotype microarrays, and antimicrobial susceptibility testing to identify genomic, metabolic and phenotypic features, and antimicrobial resistance (AMR) genes in recovered from different livestock, companion, and wildlife animals.

View Article and Find Full Text PDF

mRNA-LNP vaccines combined with tPA signal sequence elicit strong protective immunity against .

mSphere

December 2024

Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, School of Pharmacy, Chengdu University, Chengdu, China.

is a prominent Gram-negative and encapsulated opportunistic pathogen that causes a multitude of infections such as severe respiratory and healthcare-associated infections. Despite the widespread anti-microbial resistance and the high mortality rate, currently, no clinically vaccine is approved for battling . To date, messenger RNA (mRNA) vaccine is one of the most advancing technologies and are extensively investigated for viral infection, while infrequently applied for prevention of bacterial infections.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!