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Ethnogenetic analysis reveals the Bronze Age genetic affiliation of Yashkuns with West Eurasians.
Sci Rep
December 2024
Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Focusing on the Yashkun population of Gilgit-Baltistan, an administrative territory in northern Pakistan, our study investigated mtDNA haplotypes as indicators of ancient gene flow and genetic diversity. Genomic DNA was extracted and evaluated for quality using agarose gel electrophoresis. The complete control region of mtDNA (nt 16024-576) was amplified via PCR, and sequencing was performed using the Big Dye Terminator Kit on an Applied Biosystems Genetic Analyzer.
View Article and Find Full Text PDFHyperelastic models for the human zona pellucida and their implications on shear modulus estimation in the clinical practice.
Sci Rep
December 2024
Fertility and IVF Unit, Department of Obstetrics and Gynecology, Soroka University Medical Center, Beer Sheva, 151, Israel.
It has long been speculated that the mechanical properties of the human oocyte can be an indicator for oocyte viability. Recent studies have demonstrated that embryo implantation rates, following Intra-Cytoplasmic Sperm Injection (ICSI) procedures, may be increased if the shear modulus value of the oocyte Zona Pellucida (ZP) is taken into consideration during embryo transfer. The shear modulus was determined by an iterative oocyte specific finite element (FE) analysis based on the clinical ICSI data.
View Article and Find Full Text PDFOccurrence and ecological risks of antibiotics and antiparasitics in surface water in urban lakes in Hanoi city, Vietnam.
Environ Sci Pollut Res Int
December 2024
Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet Road, Cau Giay, Hanoi, Vietnam.
The presence of antibiotics in the environment is of significant concern due to their adverse effects on aquatic ecosystems. This study provides an assessment of potential ecological risks (RQ) associated with the concentrations of eight antibiotics and antiparasitics (amoxicillin-AMO, azithromycin-AZI, ciprofloxacine-CIP, ofloxacine-OFL, oxfendazole-OXF, lincomycin-LIN, sulfacetamide-SCE and sulfamethoxazole-SME) in the surface water of 13 urban lakes in Hanoi city, Vietnam during the period 2021-2023. The findings revealed considerable variations in the total concentrations of these 8 substances (T), ranging from below the method detection limit (< MDL) to 2240 ng L with an average of 330.
View Article and Find Full Text PDFMetagenomic next-generation sequencing and galactomannan testing for the diagnosis of invasive pulmonary aspergillosis.
Sci Rep
December 2024
Department of Respiratory and Critical Care Medicine, Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Weiwu Road No. 7, Zhengzhou, 450003, Henan, China.
To evaluate the diagnostic value of metagenomic next-generation sequencing (mNGS) and galactomannan (GM) testing in invasive pulmonary aspergillosis (IPA) and to compare mNGS with other diagnostic approaches (serum/bronchoalveolar lavage fluid (BALF)-GM and conventional microbiological tests (CMTs) including sputum smears and culture, BALF fungal culture, and bronchial brushing). In all, 237 patients were enrolled in this retrospective study, including 120 patients with IPA and 117 with non-IPA pulmonary infections treated at Henan Provincial People's Hospital between June 2021 and February 2024. The diagnostic performance of mNGS was compared to conventional diagnostic methods including serum GM, BALF-GM, sputum smear microscopy, sputum culture, bronchial brushings, and BALF culture.
View Article and Find Full Text PDFPrevalence of burnout and associated factors among nurses working in public hospitals, southern Ethiopia: a multi-center embedded mixed study.
Sci Rep
December 2024
School of Public Health, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
Burnout is a global concern because of its potential to affect the health of nurses and the quality of service provided. However, less consideration has been given to research in the study setting. Therefore, the study aimed to assess the prevalence of burnout and associated factors among nurses working in public hospitals of Wolaita zone, Southern Ethiopia.
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