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Effectiveness of AZD7442 (Tixagevimab/Cilgavimab) for Pre-Exposure Prophylaxis Against COVID-19 Hospitalization in Israel During the Omicron Sub-Variant Time Period.
Infect Dis Ther
January 2025
Clalit Community Division, Clalit Health Services, Tel Aviv, Israel.
Introduction: The effectiveness of AZD7442 (tixagevimab/cilgavimab) against COVID-19 hospitalizations was determined at 3 and 6 months among immunocompromised individuals in Israel during different variant circulations.
Methods: This was a retrospective cohort study using data from Clalit Health Services in Israel. Immunocompromised individuals eligible to receive AZD7442 300 mg between 15 February and 11 December 2022 were identified.
Optomechanical micro-rheology of complex fluids at ultra-high frequency.
Nat Commun
January 2025
Matériaux et Phénomènes Quantiques, Université Paris Cité, CNRS UMR 7162, Paris, France.
We present an optomechanical method for locally measuring the rheological properties of complex fluids in the ultra-high frequency range (UHF). A mechanical disk of microscale volume is used as an oscillating probe that monitors a liquid at rest, while the oscillation is optomechanically transduced. An analytical model for fluid-structure interactions is used to deduce the rheological properties of the liquid.
View Article and Find Full Text PDFThe pivotal role of sleep in mediating the effects of life stressors and healthy habits on allostatic load in mid-life adults.
Front Hum Neurosci
December 2024
Edinburgh Dementia Prevention, Centre for Clinical Brain Sciences, Outpatients Department Level 2 Western General Hospital, University of Edinburgh, Edinburgh, United Kingdom.
Objectives: We assessed the modulation of allostatic load (AL) by engagement in healthy habits and life stressors, mediated through resilience and the perceived influence of the stressors. Sleep was included as third mediator given extensive evidence associating to all the analysed factors.
Methods: Structural equation models to assess the modulation of AL by either traumatic or psychosocial stressors and healthy habits were generated with data from 620 mid-life adults (age 51.
Two cases of giant mucinous cystadenomas in postmenopausal women.
J Surg Case Rep
January 2025
Faculty of Medicine, Department of Obstetrics and Gynecology, Medical University of Sofia, Sofia, Bulgaria.
Mucinous ovarian cystadenomas are rare epithelial benign tumors that can reach significant sizes. They are often asymptomatic and are discovered incidentally during an ultrasound examination. We present two clinical cases of mucinous ovarian cystadenomas with abdominal distention.
View Article and Find Full Text PDFGenomic and Transcriptomic Profiling of Digital Papillary Adenocarcinomas Reveals Alterations in Matrix Remodeling and Metabolic Genes.
J Cutan Pathol
January 2025
Department of Pathology and Dermatology, NYU Langone Medical Center, New York, New York, USA.
Background: Digital papillary adenocarcinoma (DPAC) is a rare but aggressive cutaneous malignant sweat gland neoplasm that occurs on acral sites. Despite its clinical significance, the cellular and genetic characteristics of DPAC remain incompletely understood.
Methods: We conducted a comprehensive genomic and transcriptomic analysis of DPAC (n = 14) using targeted next-generation DNA and RNA sequencing, along with gene expression profiling employing the Nanostring Technologies nCounter IO 360 Panel.
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